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Pharmaceuticals
Volume 14
Issue 11
10.3390/ph14111122
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Review
Peer-Review Record

Reversing an Oncogenic Epithelial-to-Mesenchymal Transition Program in Breast Cancer Reveals Actionable Immune Suppressive Pathways

Pharmaceuticals 2021, 14(11), 1122; https://doi.org/10.3390/ph14111122
by Michelle M. Williams †, Sabrina A. Hafeez †, Jessica L. Christenson, Kathleen I. O’Neill, Nia G. Hammond and Jennifer K. Richer *
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Pharmaceuticals 2021, 14(11), 1122; https://doi.org/10.3390/ph14111122
Submission received: 30 September 2021 / Revised: 28 October 2021 / Accepted: 29 October 2021 / Published: 2 November 2021
(This article belongs to the Special Issue Potential Molecular Targets and Therapeutics in Triple-Negative Breast Cancer)

Round 1

Reviewer 1 Report

This is a very good review article I had great pleasure to read. I liked that you focused on the multiple aspects that characterize EMT, including metabolism, without putting the different tumor cells into sub-groups like « claudin-low » or others… instead, you highlighted the plasticity of the tumor cells. You also gave clues on different ways to alter it, opening windows on future oncologic treatments. That’s refreshing!

Author Response

Please see the attached file.

Author Response File: Author Response.pdf

Reviewer 2 Report

The Authors provide an extensive reviewe based on tackling the EMT response in TNBC. The work is very detailed and some paragraphs would require a bit of semplification/organization ot help the reader in following.  Minor revision required

Minor points: line 92 "immunocopormised" should be corrected

Author Response

Please see the attached file.

Author Response File: Author Response.pdf

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