Correlation of magnesium deficiency with C-reactive protein in elective cardiac surgery with cardiopulmonary bypass for ischemic heart disease
Abstract
Materials and methods: The data of 27 patients undergoing elective cardiac surgery with CPB for ischemic heart disease were analyzed. Measurements were taken at the baseline, i.e., 24 h before surgery (serum magnesium, CRP); time point 1, before CPB (serum, erythrocyte and cardiac tissue magnesium); time point 2, after CPB (serum, erythrocyte and cardiac tissue magnesium), and time point 3, 15–17 h after surgery (serum, erythrocyte magnesium, CRP).
Results: There was a negative correlation between baseline serum magnesium and baseline CRP (P = 0.009; r = 0.492), negative correlation between cardiac tissue magne- sium at the time point 1 and baseline CRP (P = 0.021; r = 0.443), and positive correlation between CRP at time point 3 and erythrocyte magnesium at time point 2 (P < 0.001; r = 0.637).
Conclusions: The data of our study verify that inflammatory marker CRP and magnesium concentration in serum and cardiac tissue before the surgery are inversely related in patients undergoing elective cardiac surgery with CPB. Well-planned further studies are needed to evaluate the importance of underlying magnesium deficiency on the severity of systemic inflammatory response and postoperative complications after surgery with CPB.
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Švagždienė, M.; Širvinskas, E.; Baranauskienė, D.; Adukauskienė, D. Correlation of magnesium deficiency with C-reactive protein in elective cardiac surgery with cardiopulmonary bypass for ischemic heart disease. Medicina 2015, 51, 100-106. https://doi.org/10.1016/j.medici.2015.03.003
Švagždienė M, Širvinskas E, Baranauskienė D, Adukauskienė D. Correlation of magnesium deficiency with C-reactive protein in elective cardiac surgery with cardiopulmonary bypass for ischemic heart disease. Medicina. 2015; 51(2):100-106. https://doi.org/10.1016/j.medici.2015.03.003
Chicago/Turabian StyleŠvagždienė, Milda, Edmundas Širvinskas, Dalė Baranauskienė, and Dalia Adukauskienė. 2015. "Correlation of magnesium deficiency with C-reactive protein in elective cardiac surgery with cardiopulmonary bypass for ischemic heart disease" Medicina 51, no. 2: 100-106. https://doi.org/10.1016/j.medici.2015.03.003
APA StyleŠvagždienė, M., Širvinskas, E., Baranauskienė, D., & Adukauskienė, D. (2015). Correlation of magnesium deficiency with C-reactive protein in elective cardiac surgery with cardiopulmonary bypass for ischemic heart disease. Medicina, 51(2), 100-106. https://doi.org/10.1016/j.medici.2015.03.003