Extending Neoadjuvant Care through Multi-Disciplinary Collaboration: Proceedings from the Fourth Annual Meeting of the Canadian Consortium for Locally Advanced Breast Cancer

Boileau, J.F.; Simmons, C.; Clemons, M.; Gandhi, S.; Lee, J.; Chia, S.K.; Basik, M.; Provencher, L.; Untch, M.; Brackstone, M.

doi:10.3747/co.19.1045

Open AccessMeeting Report

Extending Neoadjuvant Care through Multi-Disciplinary Collaboration: Proceedings from the Fourth Annual Meeting of the Canadian Consortium for Locally Advanced Breast Cancer

by

J.F. Boileau

^1,*,

C. Simmons

²,

M. Clemons

³,

S. Gandhi

⁴,

J. Lee

⁵,

S.K. Chia

⁶,

M. Basik

⁷,

L. Provencher

⁸,

M. Untch

⁹ and

M. Brackstone

¹⁰

¹

Odette Cancer Centre, Sunnybrook Hospital, Toronto, ON, Canada

²

Division of Medical Oncology and Hematology, St. Michael’s Hospital, Toronto, ON, Canada

³

Division of Medical Oncology, The Ottawa Hospital Cancer Centre, Ottawa, ON, Canada

⁴

Division of Medical Oncology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada

⁵

Department of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada

⁶

BC Cancer Agency, Vancouver, BC, Canada

⁷

Department of Oncology, Lady Davis Institute, Sir Mortimer B. Davis Jewish General Hospital, McGill University, Montreal, QC, Canada

⁸

Centre des Maladies du Sein Deschênes–Fabia, CHA Universitaire de Québec, Pavillon St-Sacrement, Quebec City, QC, Canada

⁹

Head of Gynecology and Gynecologic Oncology, Helios Klinikum Berlin–Buch, Berlin, Germany

¹⁰

London Regional Cancer Program, Division of General Surgery/Surgical Oncology, London, ON, Canada

^*

Author to whom correspondence should be addressed.

Curr. Oncol. 2012, 19(2), 106-114; https://doi.org/10.3747/co.19.1045

Submission received: 7 March 2012 / Revised: 7 March 2012 / Accepted: 12 March 2012 / Published: 1 April 2012

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Abstract

The use of systemic therapy before surgery (“neoadjuvant therapy”) is the standard of care for the treatment of locally advanced and nonoperable breast cancer. The advantages of neoadjuvant therapy include improved rates of breast-conserving surgery, the possibility of early measurement of response, and potentially improved outcomes for certain subgroups of high-risk patients. The use of neoadjuvant therapy in operable breast cancer is increasing, although there are no clear guidelines in Canada to help guide patient selection and management. Multidisciplinary experts in the diagnosis and treatment of locally advanced breast cancer (labc) converged at the fourth annual meeting of the Canadian Consortium for LABC (colab) to further their goals of improved standards for neoadjuvant care and clinical research through education and collaboration. Canadian clinical researchers were joined by Dr. Michael Untch of the Helios Hospital Berlin–Buch—representing the German neoadjuvant treatment groups German Gynecologic Oncology Working Group (Arbeitsgemeinschaft Gynakologische Onkologie) and German Breast Group—to discuss the advancement of research in the neoadjuvant setting and important issues of clinical care and investigator-led research. The group reached a consensus on the importance of multidisciplinary collaboration, the use of clips to mark tumour location, and core biopsy testing for the estrogen and progesterone receptors and the human epidermal growth factor receptor 2 at the time of diagnosis. Other initiatives—including creation of a prospective database, inception of the colab Neoadjuvant Network, and development of a clinical survey to evaluate current practice—continue to further the colab mandate of transforming the neoadjuvant treatment landscape in Canada.

Keywords: breast neoplasms; cancer treatment; clinical research; translational research; neoadjuvant therapy; surgery; radiation oncology; pathology

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MDPI and ACS Style

Boileau, J.F.; Simmons, C.; Clemons, M.; Gandhi, S.; Lee, J.; Chia, S.K.; Basik, M.; Provencher, L.; Untch, M.; Brackstone, M. Extending Neoadjuvant Care through Multi-Disciplinary Collaboration: Proceedings from the Fourth Annual Meeting of the Canadian Consortium for Locally Advanced Breast Cancer. Curr. Oncol. 2012, 19, 106-114. https://doi.org/10.3747/co.19.1045

AMA Style

Boileau JF, Simmons C, Clemons M, Gandhi S, Lee J, Chia SK, Basik M, Provencher L, Untch M, Brackstone M. Extending Neoadjuvant Care through Multi-Disciplinary Collaboration: Proceedings from the Fourth Annual Meeting of the Canadian Consortium for Locally Advanced Breast Cancer. Current Oncology. 2012; 19(2):106-114. https://doi.org/10.3747/co.19.1045

Chicago/Turabian Style

Boileau, J.F., C. Simmons, M. Clemons, S. Gandhi, J. Lee, S.K. Chia, M. Basik, L. Provencher, M. Untch, and M. Brackstone. 2012. "Extending Neoadjuvant Care through Multi-Disciplinary Collaboration: Proceedings from the Fourth Annual Meeting of the Canadian Consortium for Locally Advanced Breast Cancer" Current Oncology 19, no. 2: 106-114. https://doi.org/10.3747/co.19.1045

APA Style

Boileau, J. F., Simmons, C., Clemons, M., Gandhi, S., Lee, J., Chia, S. K., Basik, M., Provencher, L., Untch, M., & Brackstone, M. (2012). Extending Neoadjuvant Care through Multi-Disciplinary Collaboration: Proceedings from the Fourth Annual Meeting of the Canadian Consortium for Locally Advanced Breast Cancer. Current Oncology, 19(2), 106-114. https://doi.org/10.3747/co.19.1045

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Extending Neoadjuvant Care through Multi-Disciplinary Collaboration: Proceedings from the Fourth Annual Meeting of the Canadian Consortium for Locally Advanced Breast Cancer

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