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Gastroenterology Insights
Volume 7
Issue 1
10.4081/gi.2016.6654
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Gastroenterology Insights is published by MDPI from Volume 11 Issue 1 (2020). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

A Rare Gastrointestinal Manifestation of Systemic Primary Amyloidosis

by
Jordan Orr
1,*,
Danielle Shelnut
1,
William Ergen
2,
Arjun Nanda
2 and
Frederick Weber
2
1
Department of Internal Medicine, Tinsley Harrison Internal Medicine Residency Program, University of Alabama at Birmingham, AL, USA
2
Department of Gastroenterology and Hepatology, University of Alabama at Birmingham, AL, USA
*
Author to whom correspondence should be addressed.
Gastroenterol. Insights 2016, 7(1), 6654; https://doi.org/10.4081/gi.2016.6654
Submission received: 22 June 2016 / Accepted: 12 August 2016 / Published: 19 August 2016

Abstract

Symptomatic gastrointestinal (GI) amyloidosis is a rare manifestation of systemic amyloid light chain amyloidosis. Further, the presentation of primary GI amyloidosis without previously diagnosed systemic amyloidosis is exceptionally rare. We describe a case of a patient presenting with abdominal pain, nausea, vomiting, and weight loss later to be diagnosed with localized GI amyloidosis from underlying multiple myeloma. Unfortunately, the GI disease was insurmountable leading to her death. Amyloidosis exerts its pathology at the level of the mucosa, soft tissue, nerves, and vascular supply of the GI tract. No specific treatments for the GI complications of amyloidosis are available and supportive measures are universally employed. GI amyloidosis is not only infrequently amenable to systemic and symptomatic treatment, but has a negative impact on both quality of life and survival.
Keywords: Gastrointestinal Amyloidosis; Amyloidosis; Multiple Myeloma Gastrointestinal Amyloidosis; Amyloidosis; Multiple Myeloma

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MDPI and ACS Style

Orr, J.; Shelnut, D.; Ergen, W.; Nanda, A.; Weber, F. A Rare Gastrointestinal Manifestation of Systemic Primary Amyloidosis. Gastroenterol. Insights 2016, 7, 6654. https://doi.org/10.4081/gi.2016.6654

AMA Style

Orr J, Shelnut D, Ergen W, Nanda A, Weber F. A Rare Gastrointestinal Manifestation of Systemic Primary Amyloidosis. Gastroenterology Insights. 2016; 7(1):6654. https://doi.org/10.4081/gi.2016.6654

Chicago/Turabian Style

Orr, Jordan, Danielle Shelnut, William Ergen, Arjun Nanda, and Frederick Weber. 2016. "A Rare Gastrointestinal Manifestation of Systemic Primary Amyloidosis" Gastroenterology Insights 7, no. 1: 6654. https://doi.org/10.4081/gi.2016.6654

APA Style

Orr, J., Shelnut, D., Ergen, W., Nanda, A., & Weber, F. (2016). A Rare Gastrointestinal Manifestation of Systemic Primary Amyloidosis. Gastroenterology Insights, 7(1), 6654. https://doi.org/10.4081/gi.2016.6654

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