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Review

Mandibular Crowding: Diagnosis and Management—A Scoping Review

by
Assunta Patano
1,†,
Giuseppina Malcangi
1,†,
Alessio Danilo Inchingolo
1,†,
Grazia Garofoli
1,
Nicole De Leonardis
1,
Daniela Azzollini
1,
Giulia Latini
1,
Antonio Mancini
1,
Vincenzo Carpentiere
1,
Claudia Laudadio
1,
Francesco Inchingolo
1,*,
Silvia D’Agostino
1,2,
Daniela Di Venere
1,
Gianluca Martino Tartaglia
3,4,*,
Marco Dolci
2,
Gianna Dipalma
1,‡ and
Angelo Michele Inchingolo
1,‡
1
Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70124 Bari, Italy
2
Department of Medical, Oral and Biotechnological Sciences, University G. D’Annunzio, 66100 Chieti, Italy
3
Department of Biomedical, Surgical and Dental Sciences, School of Dentistry, University of Milan, 20100 Milan, Italy
4
UOC Maxillo-Facial Surgery and Dentistry, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, 20100 Milan, Italy
*
Authors to whom correspondence should be addressed.
†
These authors contributed equally to this work as first authors.
‡
These authors contributed equally to this work as last authors.
J. Pers. Med. 2023, 13(5), 774; https://doi.org/10.3390/jpm13050774
Submission received: 31 March 2023 / Revised: 28 April 2023 / Accepted: 28 April 2023 / Published: 29 April 2023
(This article belongs to the Special Issue Orthodontics and Oral Surgery in Personalized Medicine)
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Abstract

:
Background: Crowding is the most frequent malocclusion in orthodontics, with a strong hereditary tendency. It already occurs in pediatric age and is mainly hereditary. It is a sign of a lack of space in the arches, and is not self-correcting, but can worsen over time. The main cause of the worsening of this malocclusion is a progressive and physiological decrease in the arch perimeter. Methods: To identify relevant studies investigating the most common possible treatments for mandibular dental crowding, a comprehensive search of PubMed, Scopus and Web of Science was conducted encompassing the last 5 years (2018–2023) using the following MeSH: “mandibular crowding AND treatment” and “mandibular crowding AND therapy “. Results: A total of 12 studies were finally included. An orthodontic treatment cannot ignore the concept of “guide arch”, which concerns the lower arch, because of the objective difficulty in increasing its perimeter; the bone structure of the lower jaw is more compact than that of the upper one. Its expansion, in fact, is limited to a slight vestibularization of the incisors and lateral sectors that may be associated with a limited distalization of the molars. Conclusions: There are various therapeutic solutions available to the orthodontist, and a correct diagnosis through clinical examination, radiographs and model analysis are essential. The decision of how to deal with crowding cannot be separated from an overall assessment of the malocclusion to be treated.

1. Introduction

Crowding is a common orthodontic malocclusion with a strong hereditary tendency. It is caused by a variety of factors, including the impact of environmental and genetic factors on dental arch dimensions [1]. Dental crowding is defined as an inconsistency between tooth size and arch dimension that results in malocclusion; it occurs because of a lack of coordination between tooth size and arch dimensions [2,3,4,5]. The lower incisors are the teeth most frequently involved [6,7,8] (Figure 1).
Studies show that 46 per cent of children between 6 and 12 years old and 85% of children between 12 and 17 years old have crowding. This is because, if action is not taken, leeway space is lost, and consequently, a mild and easily resolved crowding in mixed dentition becomes stable and significant in permanent dentition [9,10,11,12]. During the third phase of the permutation, when deciduous canines and molars are replaced by permanent canines and premolars, there is a decrease in the length of the dental arch perimeter. The maximum increase in size of both dental arches occurs in the first 2 years of life; after that, the arch length increases up to 13 years in the maxilla and up to 8 years in the mandible; after this age, length decreases in both arches [13]. Crowding is thus considered a malocclusion that never self-corrects and instead worsens over time [14,15,16,17]. If present in deciduous teeth, it will worsen over the next two dental stages [18,19,20]. It generally involves 50% of individuals who were exempt in the first decade of life [21]. An orthodontic treatment cannot ignore the concept of the “guide arch”, which concerns the lower one, because of the objective difficulty in increasing its perimeter; the bone structure of the lower jaw is more compact than that of the upper one. The identification of factors that contribute to mandibular tooth crowding in mixed dentition is critical for treatment planning [22]. Several factors can be assumed to affect the development and severity of crowding, such as the direction of mandibular growth, the early loss of deciduous molars, mesiodistal tooth and arch dimensions, oral and perioral musculature and incisor and molar inclination [23]. The correction of severe mandibular crowding in mixed dentition could be carried out by extraction, distalization and surgical and non-surgical expansion of the mandible [18,24]. It is useful to emphasize that the clinician is confronted not only with crowding but also with clinical situations that are predictive of it or represent a different aspect, such as the lack of diastemas in deciduous dentition, the early loss of deciduous canines, the loss of arch length due to destructive caries, the early loss of the deciduous second molar, the appearance of teeth in ectopic position and protrusion or the accentuated retrusion of the incisors [25]. The early detection of mandibular teeth crowding is critical for interceptive orthodontic treatment planning. The aim of this study is to analyze the diagnostic methods and the treatment possibilities to solve mandibular crowding in mixed dentition.

2. Materials and Methods

2.1. Protocol and Registration

A literature review was conducted using PRISMA Extension for Scoping Reviews (PRISMA-ScR) [26].

2.2. Search Processing

To identify relevant studies investigating the most common possible treatments for mandibular dental crowding, a comprehensive search of PubMed, Scopus and Web of Science (WOS) was conducted encompassing the last 5 years (2018–2023). The following Boolean keywords were incorporated into the search strategy because they perfectly matched the aim of the investigation, which primarily focuses on the possible treatments for mandibular dental crowding: (“mandibular crowding AND treatment”) and (“mandibular crowding AND therapy”).

2.3. Eligibility Criteria

The inclusion criteria were as follows: (1) human in vivo study; (2) English language; (3) open access studies; (4) clinical studies and (5) studies analyzing the variety of therapies for mandibular dental crowding. The review followed the PICO criteria: P (patients with mandibular crowding), I (causes and treatment), C (absence of mandibular crowding) and O (efficacy of treatment options).
The exclusion criteria were as follows: (1) animal and/or in vitro studies; (2) other languages different from English; (3) not open access studies; (4) case report/series, reviews, editorials and book chapters and (5) research about diagnostic aspects of dental crowding.

2.4. Data Processing

Autor disagreements on the choice in articles were discussed and settled.

3. Results

The initial search provided a total of 833 items (PubMed n = 310, Scopus n = 282, WOS n = 241), and 346 articles remained after removing duplicates. A total of 74 articles accessed the screening phase, while 272 items were removed because 27 represented reviews, 3 were book chapters, 31 were not free full text, 3 were not in vivo, 73 were case report/series and 135 were off topic. From these products, 62 articles were additionally removed due to lack of interest in shown data, and eligibility was assigned to 12 records which were finally involved in the inclusion phase (Figure 2). Results of each study are reported in Table 1.

4. Discussion

The mandible is considered the guide arch in crowding treatment since it is the less modifiable arch [2]. In the following paragraphs, the diagnostic methods, followed by the strategies and stability of the treatment of mandibular crowding, are described.

4.1. Diagnostic Methods

Regarding the diagnosis, the lack of space in the primary dentition is a predictor to crowding. The inability to accommodate the size difference between the primary and permanent incisors is also due to a “closed” primary dentition, which prevents the mesial shift in the erupting permanent molars into a class I molar relationship during the closing of the private space [27]. Measurements for diagnosing crowding are usually taken on the plaster model with a digital caliper, both before and after treatment. Tooth size is the sum of the mesiodistal diameters of all teeth [27]. Arch length is calculated as the perpendicular distance between a line that connects the medial contact point of the first permanent molars and the most vestibular point between the lower central incisors. Crowding is measured as the difference between tooth size and arch length [27]. As result, crowding is associated with both bigger teeth and a smaller dental arch. The degree of crowding is influenced by the direction of mandibular development, early loss of primary molars, arch size, oral musculature and incisor and molar inclination [22]. Many studies have found a correlation between crowding and the direction of mandibular rotation. Extreme mandibular rotation has been linked to increased crowding, and crowding is also brought on by some growth/skeletal patterns at the start of adolescence [28]. Other factors that should not be underestimated for the diagnosis of crowding are the changes in facial morphology brought on by growth or orthodontic treatment [37]. Dental crowding is also caused by several reasons, including the impact of environmental and genetic variables on dental arch measurements such arch width, arch length and arch perimeter. Further factors influencing mesiodistal tooth width include racial characteristics, sex and inherited traits [18]. Lateral cephalograms can be used for skeletal parameters contributing to dental crowding such as effective maxillary and mandibular length, mandibular plane angle, Y axis, lower anterior face height and dental parameters such as axial inclination of the lower incisor, inclination of the lower incisor to the mandibular plane and interincisal angle [38]. Some authors have found that the use of 2D lateral cephalograms or profile photos for orthodontic measurements may not be adequately accurate. Three-dimensional computed tomography provides better frontal and three-quarter profile data for diagnosis, allowing structures to be precisely measured, aiding in analysis and diagnosis [18]. A template applied for the measurement of crowding is Little’s Irregularity Index. It denotes the total linear displacement of the six mandibular anterior teeth’s anatomical contact locations, represented in millimeters: 0 indicates perfect alignment, 1–3 mm indicates the least amount of irregularity, 4–6 mm indicates moderate abnormality, 7–9 mm indicates severe irregularity and 10 mm or more indicates very severe misalignment [30]. For treatment planning, it is crucial to identify the causes of anterior mandibular tooth crowding in mixed dentition [22]. If malocclusion is characterized by a deep bite, the cause could be skeletal, dental or both [39].
Two clinical disorders can coexist as a result of altered tooth eruption, which is the failure of a tooth to erupt into the proper location in the arch: transmigration and inclusion [40].

4.2. Prophylaxis

Primary dentition is essential for influencing the eruption of permanent teeth. Early primary tooth loss can result in undesired tooth motions and space loss in the permanent dentition [2].
It is recommended to maintain the primary dentition in the arch until exfoliation; nevertheless, if early loss is inevitable, it should be managed to minimize the negative consequences on the developing occlusion [23].
Space maintainers can be utilized for this purpose.
Early primary molar loss might result in a reduction in arch length, increasing the severity of crowding/malocclusion; therefore, in the affected patient, every effort should be made to preserve the natural leeway space [29]. The unilateral loss of a primary canine or first molar can result in a significant centerline disparity and mesial migration of the buccal segments, which is another critical clinical condition to preserve space [38]. Space maintainers are classified into three types: fixed unilateral appliances, fixed bilateral appliances and removable partial dentures. The band and loop space maintainer is one of the most prevalent permanent unilateral appliances [34]. The appliance has a band that cements to the primary second molar. It also has a loop that contacts the distal surface of the primary canine [2].
The distal shoe is another permanent unilateral appliance. A stainless-steel wire extends in front of the unerupted permanent first molar to guide it into position as it grows in. Distal shoes can only be placed on one tooth [2].
Bilateral space maintainers are used once teeth on both sides of the mouth are lost. Common types include Lingual Holding Arch, Nance Arch and Transpalatal Arch.
Removable dentures are often used for cosmetic purposes rather than to avoid space loss, particularly when anterior (front) teeth are lost [2].

4.3. Treatment

The lower jaw is considered the guiding arch in crowding therapy because it is difficult to modify its perimeter due to the more compact bone structure and the continuity with the mandibular branch, which does not allow for distalization [37,41]. In addition, the symphysis cartilage ossifies in the first year of life, so it is not possible to perform an orthopedic bone expansion, as in the upper jaw, working at the level of the median palatine suture [41,42]. The modalities of space recovery in mixed dentition are: arch perimeter increment, reduction in mesiodistal widths of teeth and serial extractions [2,43,44]. In the upper arch, the expansions are quite stable, but inferiorly, it is universally recognized that the expansion of the intercanine diameter always recurs, whereas expansion at the molar level is quite stable, which should be considered [27,45,46,47]. The space that can be recovered in the lower arch depends on the type of sector: in general, in the posterior sector, utilizing a lip bumper-style device, it is possible to recover a maximum of 2 mm of space per molar distalization in the posterior regions [48]. At the molar level in the lateral sectors, the arch length could increase by about 0.4 mm; at the canine level, the arch length increases about 0.7 mm [49]. The vestibularization of one millimeter of the incisal margin in the anterior sector results in the gain of one millimeter of arch space, or roughly a ratio of one to one (changing the arch form) [47]. Schwarz’s appliance (Figure 3) and lip bumper (Figure 4) are two commonly used appliances for increasing lower dental arch dimensions [50]. In their study, Vincenzo Quinzi et al. compared the effects of these appliances on reducing mandibular crowding by increasing lower arch dimensions [27]. The study included twenty subjects (10 males and 10 females). Ten patients were treated with Schwarz’s appliance, and ten with lip bumper. The Schwarz appliance was more effective in increasing intercanine arch dimensions and arch perimeter, although the lip bumper reached a greater increase in arch length [27]. Since the 1970s, there have been reports of spontaneous changes in mandibular dentition caused by maxillary expansion [31,51]. Di Ventura et al. assessed the consequences of rapid maxillary expansion (RME) anchored to primary molars on the mandibular arch. A total of 54 patients were recruited for this study and divided into two groups: a test group (21 patients, 7.4 ± 1.2 years) who underwent RME, and a control group (17 patients, 7.3 ± 1.1 years old) who did not receive any treatment. The results of this study showed a significant increase in interdental width in the lower arch after 9 months of RME therapy [31]. Olivia Griswold et al. evaluated the changes in sagittal mandibular incisors’ position in response to lip bumper therapy using CBCT [32]. In this study, the authors compared a group that was treated only with rapid maxillary expansion (experimental group) and an RME + LB (lip bumper) group (control group) [32]. The CBCTs were placed in 3D on the mandibular structure, and the angular and linear alterations in the mandibular incisors throughout LB therapy were assessed. In the investigation, there was no statistically significant difference in the degree of mandibular incisor protrusion between the two groups; the lip bumper did not generate substantial proclination, protrusion or extrusion of the mandibular incisors. [13]. Air-rotor stripping (ARS) (Figure 5) is a technique for creating space during the mixed dentition period by reducing interproximal enamel thickness. Yahya B. Nakhjavani et al. assessed the efficacy of the mesial stripping of mandibular deciduous canines for the correction of rotated and lingually erupted lateral incisors in 42 patients with <3 mm mandibular crowding [33]. In this study, the mesial stripping of mandibular primary canines resulted in full crowding correction; in just few cases, the amount of crowding did not reach zero, and a small crowding in the range of 0.06 to 0.1 mm remained [33]. The extraction of all the first premolars with subsequent orthodontic treatment is the most used method to relieve dental crowding [52]. The importance and timing of extraction as a component of orthodontic therapy for late incisor crowding have been well investigated [35]. No difference in late incisor crowding is shown by the data, regardless of whether serial extraction or early or late premolar extraction is performed prior to orthodontic treatment. Additionally, selecting a non-extraction orthodontic procedure has been linked to post-retention crowding [35]. Maurits Persson et al. investigated changes in the mandibular incisor area from early adolescence to late adulthood in patients with a class I crowding malocclusion treated in the mixed dentition by the extraction of all first premolars without subsequent orthodontic treatment [35]. The extraction group included 24 subjects who had all their first premolars extracted at a mean age of about 11.5 years to treat a class I space deficiency malocclusion. The control group included 21 subjects who had normal occlusions at the age of 13 years [35]. The extraction group showed no improvements in lower incisor irregularity, and a significant increase in lower tooth space insufficiency into adulthood. Lower incisor irregularity and space shortage developed significantly in the control group throughout late adulthood [35]. Premolar extraction is the sole treatment option for severe crowding in a class I occlusion, allowing for spontaneous adjustments and more stable incisor alignment in late adulthood, according to the authors [35] (Table 2).

4.4. Treatment Stability

Long-term stability after orthodontic treatment is a challenge for orthodontists. The retention of lower incisors after alignment is variable, and the severity of the relapse may not be predicted precisely. In the literature, it has been reported that post-treatment relapse occurs in 70% of cases [34]. The dental arches are parts of the organism under constant movement and load during their function. In a situation of balance, the shape of the dental arch remains normal. When tensegrity is lost, a new shape is obtained to gain the new balanced position. Tooth alignment is always accompanied by an increase in intercanine width or protrusion, unless interproximal reduction or extractions are performed [34,35]. Some authors have suggested that the post-treatment position of mandibular incisors may be influenced by several factors, such as initial crowding, treatment procedures, patient cooperation and soft tissue growth [34,35,36]. Outcome and stability between cases treated without extraction and cases treated with extraction of a mandibular incisor or mandibular premolars were assessed by Mahmoudzadeh et al. The study showed that there was no significant correlation between treatment modality and changes in the incisor alignment post-retention. In a retrospective study by Purva Verma et al., 32 subjects treated for mandibular dental crowding were examined at 1 year of follow up. Patients treated with passive self-ligation non-extraction protocol showed worse stability in intercanine width and changes in lower incisor inclination than patients treated with conventional ligation lower incisor extraction protocol [34]. It is likely that arch width and length decrease over time, probably due to the mesial drift of the posterior teeth [34]. In a 50-year case-control study, a comparison between patients undergoing extraction of all first premolars in early adolescence and untreated subjects with a normal alignment was carried out. According to this study, patients treated with extractions showed better stability in lower alignment into late adulthood than untreated subjects, who developed lower incisor crowding with age [35]. Barbert et al. stated that the post-treatment 3 × 3 bonded retainer is useful to prevent the relapse of mandibular crowding. Sixteen patients treated with mandibular incisor extraction were examined at 1 year of follow up: patients without a retainer showed a significant relapse when compared to the retainer group [36].
This review has some limitations. The studies found are few and heterogeneous. Furthermore, it is an analysis conducted over a period of five years. Finally, there was no assessment of the quality of the studies.

5. Conclusions

In dental crowding therapy, it is important to quantify the lack of space in the dental arch in order to choose an appropriate orthodontic therapy. A correct diagnosis is obtained through clinical examination, X-rays, cephalometric analysis and study models. CBCT provides additional support for the diagnosis. The mandible is considered the guiding arch in orthodontic therapy, as it is not very modifiable. The correction of severe mandibular crowding in mixed dentition can be achieved by extraction, distalization and surgical and non-surgical expansion of the mandible. The degree of crowding is influenced by the direction of mandibular development, early loss of primary molars, arch size, buccal musculature and the inclination of the incisors and molars. In mixed dentition, there are various ways to recover space that can be combined: maintaining the leeway space, lengthening the arch perimeter, resorting to extractions, stripping, etc. Decisions on crowding management must be made in the context of an overall assessment of the malocclusion to be treated.

Author Contributions

Conceptualization, A.P., A.M.I., C.L., N.D.L. and A.D.I.; Methodology, D.A., G.G., M.D., S.D. and G.M.T.; Software, D.A., A.D.I., A.M., G.L., D.D.V., G.D., V.C. and G.M.; Validation, C.L., F.I., G.M.T. and D.D.V.; Formal analysis, A.P., N.D.L., A.M.I., A.D.I. and A.M.; Resources, G.L., A.M.I., G.D. and D.D.V.; Data curation, G.D., D.D.V., G.M.T. and F.I.; Writing—original draft preparation, A.M.I., M.D. and G.M.; Writing—review and editing, A.P., G.G., V.C., G.L. and A.M.I.; Visualization, G.L., A.M., G.D., S.D. and G.M.; Supervision, A.P., G.D., F.I. and G.M.; Project administration, G.M., F.I. and G.D. All authors have read and agreed to the published version of the manuscript.

Funding

This research received no external funding.

Institutional Review Board Statement

Not applicable.

Informed Consent Statement

Not applicable.

Data Availability Statement

Not applicable.

Conflicts of Interest

The authors declare no conflict of interest.

Abbreviations

RMERapid maxillary expansion
LBLip bumper
ARSAir-rotor stripping
CBCTCone beam computed tomography

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Jpm 13 00774 g001 550
Figure 1. Crowding of the permanent mandibular incisors.
Figure 1. Crowding of the permanent mandibular incisors.
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Figure 2. PRISMA ScR flowchart.
Figure 2. PRISMA ScR flowchart.
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Figure 3. Schwarz’s appliance.
Figure 3. Schwarz’s appliance.
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Figure 4. Lip bumper.
Figure 4. Lip bumper.
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Figure 5. Air-rotor stripping (ARS).
Figure 5. Air-rotor stripping (ARS).
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Table
Table 1. Results table.
Table 1. Results table.
Authors (Year) Type of Study Aim of the Study Materials Results
Partha Jyoti Das et al., 2017 [18]Cross-sectional study To assess dental crowding in relation to mesiodistal crown widths and arch lengthsA total of 132 patients were separated into two groups: crowded and non-packed, each of which had 66 subjects (33 males and 33 females), all of whom were between the ages of 15 and 35 and had been sent to the radiology department for a brain computed tomography scan.The results of this study showed that in South Indian men, both the factors—mesiodistal crown width and arch dimensions—contributed to dental crowding, and the crowded dentition had larger mesiodistal teeth and smaller arch dimensions. However, in women, neither of these factors was found to be the cause of crowding.
Vincenzo Quinzi, Silvia Caruso et al., 2020 [27]Prospective pilot study This prospective study’s objective was to evaluate dental crowding and arch measurements before and after lip bumper versus Schwarz’s appliance therapy.The present study investigated the pre- and post-treatment orthodontic records of 20 patients (10 males and 10 females). The following criteria were used for inclusion: first/second molar class malocclusion; mild to moderate (4–6 mm) crowding of the mandibular arch; mixed dentition; and age 9 years at the start of therapy.Both a Schwarz appliance and a lip bumper are effective in lessening crowding in mixed dentition. The expansion of the dental arch is the reason for this improvement; however the two appliances’ allocation of the resulting space differed slightly.
Fathima Bareera Rezvi, Ravindra Kumar Jain et al., 2019 [28]Retrospective cross-sectional study To assess the frequency of mandibular anterior tooth crowding in patients with mixed dentition who present to a university hospital in Chennai.A total of 3652 participants who attended the Saveetha Dental College’s Orthodontics department between June 2019 and March 2020 were included in the research. Data were retrieved from digital records.Crowding of the mandibular anterior teeth was substantially correlated with age, although there was no correlation with gender.
Priyanka Satra, Gauri Vichare et al., 2022 [29]Retrospective studyTo evaluate, quantify and compare the maxillary and mandibular effective base lengths, arch lengths and the degree of dental crowding in individuals with various vertical development patterns.A sample of 100 study models (aged 16 to 25) and pre-treatment lateral cephalograms was randomly chosen. Based on the measurement of the gonial angle, the sample was separated into two groups: clockwise (50) and anticlockwise (50) rotation.Dental crowding is caused by the mandible rotating clockwise as well as skeletal and dental variables including shorter effective base lengths and shorter arch lengths, respectively.
J. Antoszewska-Smith, M. Bohater et al., 2017 [30]Research articleThis study attempted to determine the validity of Little’s Irregularity Index (LII) as a measure of the stability of treatment results in individuals with crowded mandibular incisors.Digital dental casts of 302 individuals were used to create the material. There were 201 women and 101 men, between the ages of 21 and 39, with late crowding of the mandibular front teeth before treatment. All patients were divided into three groups after Little’s Irregularity Index measurement.Thirty years after its introduction, LII has shown to be a dependable measure that enables the choice in the best treatment options.
Di Ventura et al.,2019 [31]Retrospective study Evaluated the effect of RME on mandibular arch in mixed dentition.Patients (n = 54) were divided into two groups: (n = 21) patients treated with RME; (n = 17) patients that did not receive any treatment. The results of this study show a significant increase in interdental width in the lower arch after 9 months of RME therapy.
Olivia Griswold et al., 2022 [32]Retrospective study Evaluated the changes in sagittal mandibular incisors’ position in response to lip bumper therapy using CBCT (cone beam computed tomography).Patients (n = 34) were divided in two groups: rapid maxillary expansion group with no lower treatment (experimental group) and an RME (rapid maxillary expansion) + LB (lip bumper) group (control group).There was no statistically significant difference in the amount of mandibular incisor protrusion between the two groups.
Nakhjavani et al., 2017 [33]Clinical trial The purpose of this study was to determine the effectiveness of mesial stripping of mandibular deciduous canines for the correction of rotated and lingually erupted lateral incisors.A total of 42 patients with <3 mm mandibular crowding were included and followed up for 5 months.Mesial stripping of mandibular primary canines resulted in full crowding correction; in just a few cases, the amount of crowding did not reach zero.
Purva Verma et al., 2022 [34] Retrospective study To compare the stability of mandibular anterior crowding after correction with two treatment protocols.Patients (n = 32) were divided into two groups: (n = 15) patients treated with passive self-ligation non-extraction protocol; (n = 17) patients treated with conventional ligation lower incisor extraction protocol.
Changes in intermolar width, intercanine width, Little’s Irregularity Index and mandibular incisor inclination at pretreatment, post-debonding and 1 year post-debonding were evaluated.		 Change in intermolar width was similar in both groups.
The relapse in intercanine width and inclination of lower incisor was significantly greater in patients treated in non-extraction protocol.
Mahmoudzadeh et al., 2022 [27]Cross-sectional studyTo compare the relapse tendency of crowding in patients treated with different protocols.Patients (n = 120) were treated with fixed appliances and followed up after 3.5 years.
Patients were divided into three groups: patients treated without extraction, patients treated with single extraction and patients treated with premolar extraction.		Treatment modality does not influence the post-treatment relapse.
Persson et al., 2022 [35]Longitudinal, case-control studyTo assess the effects of early extraction of four premolars on the crowding of lower incisors after 50 years of follow-up.Patients (n = 45) were divided into: a group of patients who underwent extraction of all first premolars (n = 24) and a group of untreated patients with a normal occlusion (n = 21).Lower incisor alignment remains unchanged into late adulthood in patients who have all first premolars removed compared with untreated subjects.
Berbert et al., 2020 [36]Retrospective studyTo evaluate if the 3 × 3 bonded mandibular retainer influences the relapse of crowding at 1 year of follow up.Patients (n = 16) were treated with mandibular incisor extraction and were divided into: patients who did not present the 3x3 bonded retainer (n = 9) and patients with 3 × 3 bonded retainer (n = 7).Patients with 3x3 bonded retainer showed good stability in mandibular incisor alignment in comparison to patients without retainer.
Table
Table 2. Summary table.
Table 2. Summary table.
Methods of Treatment of Mandibular CrowdingGoal
Schwarz’s appliance
Lip bumper appliance		To increment the perimeter of mandibular arch
SlicingIt is a simple procedure that recovers the Leeway space in advance, that is, before the exchange of the milk molars and without resorting to any orthodontic appliance
Serial extractionTo create space in the mixed dentition for the eruption of permanent teeth into more favorable positions over basal bone to prevent or reduce the complexity of future orthodontic treatment in the permanent dentition
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Patano, A.; Malcangi, G.; Inchingolo, A.D.; Garofoli, G.; De Leonardis, N.; Azzollini, D.; Latini, G.; Mancini, A.; Carpentiere, V.; Laudadio, C.; et al. Mandibular Crowding: Diagnosis and Management—A Scoping Review. J. Pers. Med. 2023, 13, 774. https://doi.org/10.3390/jpm13050774

AMA Style

Patano A, Malcangi G, Inchingolo AD, Garofoli G, De Leonardis N, Azzollini D, Latini G, Mancini A, Carpentiere V, Laudadio C, et al. Mandibular Crowding: Diagnosis and Management—A Scoping Review. Journal of Personalized Medicine. 2023; 13(5):774. https://doi.org/10.3390/jpm13050774

Chicago/Turabian Style

Patano, Assunta, Giuseppina Malcangi, Alessio Danilo Inchingolo, Grazia Garofoli, Nicole De Leonardis, Daniela Azzollini, Giulia Latini, Antonio Mancini, Vincenzo Carpentiere, Claudia Laudadio, and et al. 2023. "Mandibular Crowding: Diagnosis and Management—A Scoping Review" Journal of Personalized Medicine 13, no. 5: 774. https://doi.org/10.3390/jpm13050774

APA Style

Patano, A., Malcangi, G., Inchingolo, A. D., Garofoli, G., De Leonardis, N., Azzollini, D., Latini, G., Mancini, A., Carpentiere, V., Laudadio, C., Inchingolo, F., D’Agostino, S., Di Venere, D., Tartaglia, G. M., Dolci, M., Dipalma, G., & Inchingolo, A. M. (2023). Mandibular Crowding: Diagnosis and Management—A Scoping Review. Journal of Personalized Medicine, 13(5), 774. https://doi.org/10.3390/jpm13050774

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