Versatility of Glutathione Transferase Proteins
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References
- Mannervik, B. Five Decades with Glutathione and the GSTome. J. Biol. Chem. 2012, 287, 6072–6083. [Google Scholar] [CrossRef] [PubMed]
- Boyland, E.; Chasseaud, L.F. The Role of Glutathione and Glutathione S-Transferases in Mercapturic Acid Biosynthesis. Adv. Enzymol. Relat. Areas Mol. Biol. 1969, 32, 173–219. [Google Scholar] [CrossRef] [PubMed]
- Berhane, K.; Mannervik, B. Inactivation of the Genotoxic Aldehyde Acrolein by Human Glutathione Transferases of Classes Alpha, Mu, and Pi. Mol. Pharmacol. 1990, 37, 251–254. [Google Scholar]
- Perperopoulou, F.; Pouliou, F.; Labrou, N.E. Recent Advances in Protein Engineering and Biotechnological Applications of Glutathione Transferases. Crit. Rev. Biotechnol. 2018, 38, 511–528. [Google Scholar] [CrossRef] [PubMed]
- Cromer, B.A.; Morton, C.J.; Board, P.G.; Parker, M.W. From Glutathione Transferase to Pore in a CLIC. Eur. Biophys. J. 2002, 31, 356–364. [Google Scholar] [CrossRef] [PubMed]
- Oakley, A. Hidden Glutathione Transferases in the Human Genome. Biomolecules 2023, 13, 1240. [Google Scholar] [CrossRef]
- Jumper, J.; Evans, R.; Pritzel, A.; Green, T.; Figurnov, M.; Ronneberger, O.; Tunyasuvunakool, K.; Bates, R.; Žídek, A.; Potapenko, A.; et al. Highly Accurate Protein Structure Prediction with AlphaFold. Nature 2021, 596, 583–589. [Google Scholar] [CrossRef]
- Evans, R.; O’Neill, M.; Pritzel, A.; Antropova, N.; Senior, A.; Green, T.; Žídek, A.; Bates, R.; Blackwell, S.; Yim, J.; et al. Protein Complex Prediction with AlphaFold-Multimer. bioRxiv 2022. [Google Scholar] [CrossRef]
- Mannervik, B.; Morgenstern, R. Comprehensive Toxicology, 4th ed.; Elsevier: New York, NY, USA, 2024; Chapter 10.16. [Google Scholar]
- Mazari, A.; Zhang, L.; Ye, Z.; Zhang, J.; Tew, K.; Townsend, D. The Multifaceted Role of Glutathione S-Transferases in Health and Disease. Biomolecules 2023, 13, 688. [Google Scholar] [CrossRef]
- Tew, K.D. Glutathione-Associated Enzymes in Anticancer Drug Resistance. Cancer Res. 1994, 54, 4313–4320. [Google Scholar] [CrossRef]
- Kupreienko, O.; Pouliou, F.; Konstandinidis, K.; Axarli, I.; Douni, E.; Papageorgiou, A.; Labrou, N. Inhibition Analysis and High-Resolution Crystal Structure of Mus musculus Glutathione Transferase P1-1. Biomolecules 2023, 13, 613. [Google Scholar] [CrossRef] [PubMed]
- Russell, T.; Richardson, D. Glutathione-S-Transferases as Potential Targets for Modulation of Nitric Oxide-Mediated Vasodilation. Biomolecules 2022, 12, 1292. [Google Scholar] [CrossRef] [PubMed]
- Tsuchida, S.; Maki, T.; Sato, K. Purification and Characterization of Glutathione Transferases with an Activity toward Nitroglycerin from Human Aorta and Heart. Multiplicity of the Human Class Mu Forms. J. Biol. Chem. 1990, 265, 7150–7157. [Google Scholar] [CrossRef] [PubMed]
- Andrabi, S.M.; Sharma, N.S.; Karan, A.; Shahriar, S.M.S.; Cordon, B.; Ma, B.; Xie, J. Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications. Adv. Sci. 2023, 10, e2303259. [Google Scholar] [CrossRef] [PubMed]
- De Maria, F.; Pedersen, J.Z.; Caccuri, A.M.; Antonini, G.; Turella, P.; Stella, L.; Bello, M.L.; Federici, G.; Ricci, G. The Specific Interaction of Dinitrosyl-Diglutathionyl-Iron Complex, a Natural NO Carrier, with the Glutathione Transferase Superfamily: Suggestion for an Evolutionary Pressure in the Direction of the Storage of Nitric Oxide. J. Biol. Chem. 2003, 278, 42283–42293. [Google Scholar] [CrossRef] [PubMed]
- Scian, M.; Paço, L.; Murphree, T.; Shireman, L.; Atkins, W. Reversibility and Low Commitment to Forward Catalysis in the Conjugation of Lipid Alkenals by Glutathione Transferase A4-4. Biomolecules 2023, 13, 329. [Google Scholar] [CrossRef] [PubMed]
- Awasthi, Y.C.; Ramana, K.V.; Chaudhary, P.; Srivastava, S.K.; Awasthi, S. Regulatory Roles of Glutathione-S-Transferases and 4-Hydroxynonenal in Stress-Mediated Signaling and Toxicity. Free Radic. Biol. Med. 2017, 111, 235–243. [Google Scholar] [CrossRef] [PubMed]
- Schwartz, M.; Boichot, V.; Fraichard, S.; Muradova, M.; Senet, P.; Nicolai, A.; Lirussi, F.; Bas, M.; Canon, F.; Heydel, J.; et al. Role of Insect and Mammal Glutathione Transferases in Chemoperception. Biomolecules 2023, 13, 322. [Google Scholar] [CrossRef]
- Ben-Arie, N.; Khen, M.; Lancet, D. Glutathione S-Transferases in Rat Olfactory Epithelium: Purification, Molecular Properties and Odorant Biotransformation. Biochem. J. 1993, 292, 379–384. [Google Scholar] [CrossRef]
- Koirala, B.K.S.; Moural, T.; Zhu, F. Functional and Structural Diversity of Insect Glutathione S-Transferases in Xenobiotic Adaptation. Int. J. Biol. Sci. 2022, 18, 5713–5723. [Google Scholar] [CrossRef]
- Wiktelius, E.; Stenberg, G. Novel Class of Glutathione Transferases from Cyanobacteria Exhibit High Catalytic Activities Towards Naturally Occurring Isothiocyanates. Biochem. J. 2007, 406, 115–123. [Google Scholar] [CrossRef]
- Mocchetti, E.; Morette, L.; Mulliert, G.; Mathiot, S.; Guillot, B.; Dehez, F.; Chauvat, F.; Cassier-Chauvat, C.; Brochier-Armanet, C.; Didierjean, C.; et al. Biochemical and Structural Characterization of Chi-Class Glutathione Transferases: A Snapshot on the Glutathione Transferase Encoded by sll0067 Gene in the Cyanobacterium Synechocystis sp. Strain PCC 6803. Biomolecules 2022, 12, 1466. [Google Scholar] [CrossRef] [PubMed]
- Mannervik, B.; Ismail, A.; Lindström, H.; Sjödin, B.; Ing, N.H. Glutathione Transferases as Efficient Ketosteroid Isomerases. Front. Mol. Biosci. 2021, 8, 765970. [Google Scholar] [CrossRef]
- Hubert, S.; Samollow, P.; Lindström, H.; Mannervik, B.; Ing, N. Conservation of Glutathione Transferase mRNA and Protein Sequences Similar to Human and Horse Alpha Class GST A3-3 across Dog, Goat, and Opossum Species. Biomolecules 2023, 13, 1420. [Google Scholar] [CrossRef]
- Musdal, Y.; Ismail, A.; Sjödin, B.; Mannervik, B. Potent GST Ketosteroid Isomerase Activity Relevant to Ecdysteroidogenesis in the Malaria Vector Anopheles gambiae. Biomolecules 2023, 13, 976. [Google Scholar] [CrossRef] [PubMed]
- Chanut-Delalande, H.; Hashimoto, Y.; Pelissier-Monier, A.; Spokony, R.; Dib, A.; Kondo, T.; Bohère, J.; Niimi, K.; Latapie, Y.; Inagaki, S.; et al. Pri Peptides Are Mediators of Ecdysone for the Temporal Control of Development. Nat. Cell Biol. 2014, 16, 1035–1044. [Google Scholar] [CrossRef] [PubMed]
- Enya, S.; Ameku, T.; Igarashi, F.; Iga, M.; Kataoka, H.; Shinoda, T.; Niwa, R. A Halloween Gene Noppera-Bo Encodes a Glutathione S-Transferase Essential for Ecdysteroid Biosynthesis via Regulating the Behaviour of Cholesterol in Drosophila. Sci. Rep. 2014, 4, 6586. [Google Scholar] [CrossRef]
- Ebihara, K.; Niwa, R. Compounds Inhibiting Noppera-bo, a Glutathione S-transferase Involved in Insect Ecdysteroid Biosynthesis: Novel Insect Growth Regulators. Biomolecules 2023, 13, 461. [Google Scholar] [CrossRef]
- Inaba, K.; Ebihara, K.; Senda, M.; Yoshino, R.; Sakuma, C.; Koiwai, K.; Takaya, D.; Watanabe, C.; Watanabe, A.; Kawashima, Y.; et al. Molecular Action of Larvicidal Flavonoids on Ecdysteroidogenic Glutathione S-Transferase Noppera-Bo in Aedes aegypti. BMC Biol. 2022, 20, 43. [Google Scholar] [CrossRef]
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Mannervik, B. Versatility of Glutathione Transferase Proteins. Biomolecules 2023, 13, 1749. https://doi.org/10.3390/biom13121749
Mannervik B. Versatility of Glutathione Transferase Proteins. Biomolecules. 2023; 13(12):1749. https://doi.org/10.3390/biom13121749
Chicago/Turabian StyleMannervik, Bengt. 2023. "Versatility of Glutathione Transferase Proteins" Biomolecules 13, no. 12: 1749. https://doi.org/10.3390/biom13121749
APA StyleMannervik, B. (2023). Versatility of Glutathione Transferase Proteins. Biomolecules, 13(12), 1749. https://doi.org/10.3390/biom13121749