Gut Permeability in Monogastric and Polygastric Animals
A special issue of Animals (ISSN 2076-2615).
Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 2832
Special Issue Editor
Special Issue Information
Dear Colleagues,
“The gut of any animal relies on the ability to prevent luminal pathogens from traversing the mucosal barrier and yet simultaneously maintaining efficient digestion and absorption of nutrients. In order to achieve this, requires precise coordination between the different components of this “first-line defence” barrier. Several factors that contribute to mucosal barrier integrity are (1) secreted antimicrobial proteins and peptides, such as defensins and lyzozyme (2) epithelial tight junctions, critical for maintenance of gut permeability (3) IgA secretion through multiple follicular and extrafollicular pathways and (4) the overlying mucus layer, formed through the packaging and secretion of polymeric mucin glycoproteins by goblet cells. These aspects of the intestinal environment are intricately linked to one another, and unfavourable shifts can lead to poor performance. The early establishment of a healthy microbiota and intestinal environment is critical to the long-term health status of animals.
In this special issue of Animals, we focus on gut permeability and factors that can impact intestinal barrier integrity. We also highlight current research in developing novel strategies to improve gut integrity and prevention of potential enteric disorders in both mono and poly-gastric species”.
Dr. Rebecca Forder
Guest Editor
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