Antifungal Strategies: Epidemiological Approaches, Mechanisms and Resistance in Fungal Pathogens
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Fungi and Their Metabolites".
Deadline for manuscript submissions: 31 July 2025 | Viewed by 50
Special Issue Editors
Interests: clinical microbiology; medical mycology; opportunistic mycoses; yeasts of the genus Candida; trichosporon; filamentous fungi; mucorales; dermatophytes; sporotrichosis; virulence factors; molecular epidemiology of fungal pathogens; infectious diseases
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Interests: virulence factors of microsporum canis and trichophyton rubrum; yeast of the genus Candida and other yaest; sporotrichosis; infectious diseases; drug resistance
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2. Department of Health Sciences, University of Vigo, Campus of Vigo, As Lagoas, 36310 Vigo, Spain
Interests: hidradenitis; psoriasis; atopic dermatitis, biologic drugs; dermoscopy; ultrasonography; mycology; psicodermatology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
There are several drugs (azoles, echinocandins, polyenes, etc.) used in and out-of-hospital for the treatment of superficial, subcutaneous, systemic, and opportunistic mycoses. Unfortunately, delay in diagnosis and susceptibility to treatment can result in serious consequences (disability or mortality) for patients, especially for immunocompromised patients, as well as unnecessary costs to health systems. There is evidence of an increase in the resistance of these pathogens to the various antifungal drugs, which differs by region worldwide. This is because the expression of genes that induce phenotypic resistance factors (catalase, superoxide dismutase, elastase, phospholipases, hemolysins, lipases, subtilisins, etc.) have been described with differences between species and according to geographical locations. Likewise, fungi whose teleomorphic or sexual state has been identified have shown a certain level of genotypic variability, leading to different levels of resistance to the same antifungal. More studies of the impact of these diseases in the health sector are needed to better understand the regional characteristics of each one and to facilitate care by obtaining favorable results during empirical treatments.
This Special Issue will focus on original and review articles describing antifungal strategies, including the epidemiological and clinical data of mycological infections, in silico studies for molecular targets involved in antifungal resistance, in vitro and in vivo studies focused on molecular/cellular mechanisms associated with Mycoses, studies of natural products, synthetic compounds and repositioning of drugs for the treatment in fungal infections.
Dr. Erick Martinez-Herrera
Prof. Dr. Rodolfo Pinto-Almazán
Prof. Dr. Carmen Rodríguez-Cerdeira
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antifungal strategies
- epidemiology
- antifungal resistance
- antifungal mechanisms
- resistance genes
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