Impact of Oxidative Stress and Mitochondrial Dysfunction on the Regulation of Brain, Heart, Lung and Vascular Functions
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 1784
Special Issue Editor
Interests: oxidative stress; endothelial dysfunction; vascular dysfunction; systemic hypertension; pulmonary hypertension; mitochondrial dysfunction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Redox and mitochondrial pathways play a critical role both in the homeostasis and the pathogenesis of cardiovascular disease, stroke, lung disease, cognitive decline and dementia; these diseases represent enormous healthcare and economic burden for society. Understanding the ethology of these conditions is critical to increase the healthspan of individuals and reduce the rates of morbidity and mortality. Multiple risk factors contribute to these pathological conditions. The old paradigm was to focus on systemic metabolic disorders; however, recent studies indicate that cell-specific mitochondria/metabolic dysregulation in the vascular cells promote pathological conditions independently from systemic alterations. This new paradigm provides novel insight into these pathways, such as accelerated vascular aging and crosstalk between cardiac and neurological conditions.
This Special Issue aims to be a platform where cross-disciplinary efforts addressing the gap of knowledge in this field could be disseminated.
Dr. Anna Dikalova
Guest Editor
Manuscript Submission Information
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Keywords
- oxidative stress
- mitochondrial dysfunction
- cardiovascular disease
- vascular dysfunction
- ageing
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