Advanced Radiopharmaceuticals for Cancer Imaging and Therapy
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Biomedical Engineering".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 364
Special Issue Editor
Interests: novel radiothepeutic isotopes for PET imaging and therapy; multimodal imaging; targetted radiotherapy; upconversion luminescence
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Advanced radiopharmaceuticals are transforming cancer imaging and therapy by providing highly targeted treatments. Targeted Alpha Therapy (TAT) utilizes alpha-emitting radionuclides to deliver potent radiation doses directly to cancer cells, sparing surrounding healthy tissue. This precision is achieved by linking radionuclides to targeting vectors, such as monoclonal antibodies, which specifically bind to tumor cells. TAT is particularly effective against micrometastases and tumors resistant to conventional therapies.
Radiotherapy using beta-emitting radionuclides like Lutetium-177 and Yttrium-90 is another promising approach. These radionuclides emit beta particles, which are effective in treating larger tumors. Beta-emitting radiopharmaceuticals are often used in conjunction with targeting molecules to enhance their delivery to cancer cells. This method allows for the treatment of a wide range of cancers, including neuroendocrine tumors and lymphomas.
Positron Emission Tomography (PET) imaging isotopes play a crucial role in cancer diagnosis and treatment planning. PET imaging provides detailed metabolic and molecular information about tumors, enabling precise staging and monitoring of treatment response. Common PET isotopes include Fluorine-18 and Gallium-68, which are used to visualize tumor activity and guide therapeutic decisions.
Overall, the integration of TAT, beta-emitting radionuclides, and PET imaging isotopes represents a significant advancement in personalized cancer therapy, offering improved outcomes through precise targeting and innovative imaging technologies.
Dr. Arif Gulzar
Guest Editor
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Keywords
- targetted alpha therapy
- radiotherapy
- positron emission tomography
- isotopes
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