Recent Advance and Applications in Chip Calorimetry
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Chemical and Molecular Sciences".
Deadline for manuscript submissions: closed (20 February 2022) | Viewed by 7267
.png)
Special Issue Editors
Interests: chip calorimetry; scientific instrumentation; bio-calorimetry
Special Issue Information
Dear Colleagues,
Chip calorimeters are modern, highly miniaturized representatives of an old and very fundamental method used in physical chemistry and related sciences. They are characterized by the integration of the essential functional elements of a calorimeter, such as sensors for the measurement of temperatures and temperature differences, calibration heaters, sample containers, and heat sinks in a solid-state device, generally a silicon chip. The micro-techniques used for the preparation of the heat power transducers in chip calorimeters have led to high signal resolution and extremely small signal time constants.
In the past twenty years of chip calorimeter development, two basic application directions have emerged. The first is the reduction of the sample mass and addenda heat capacity by several orders of magnitude, allowing extremely high heating and cooling rates, as well as temperature modulation at higher frequencies. As a consequence, opportunities have arisen for the study of phase transitions in the smallest samples, such as nanocrystals and thin films. The availability of commercial equipment is a testimony to the fact that this method is now well established in materials science. Isothermally operated chip calorimeters are of particular interest for biological applications. Here, the focus is particularly on the use of small sample volumes and high sample throughput. Since variations in the metabolic activity of living materials are generally accompanied by changes in metabolic heat production, drug effects in cell cultures, tissue samples, as well as in intact mini-organs and small living organisms can be rapidly detected using chip calorimeters. Extremely miniaturized temperature measurement techniques allow the localization of metabolic processes within single living cells based on their different heat output contributions.
Chip calorimetry is still a rapidly developing field of research. This Special Issue on this area is intended to provide an overview of the current state-of-the-art, as well as the possibilities and limitations, and to encourage broader applications. Contributions presenting new results are very welcome, especially from the fields of ultrafast scanning calorimetry and bio-medical diagnostics in the broadest sense, including single-cell thermometry.
Dr. Johannes Lerchner
Prof. Dr. Christoph Schick
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- ultra-fast scanning calorimetry
- phase transition
- nano-samples
- thin-films
- metabolic heat production
- metabolic drug responses
- single-cell thermometry
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
