Engineering Stem Cells for Cancer Treatment and Infection
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Regenerative Engineering".
Deadline for manuscript submissions: 28 February 2025 | Viewed by 119
Special Issue Editors
Interests: radiation oncology; radiation therapy; GI-ARS; cell therapy
Special Issue Information
Dear Colleagues,
The integration of stem cell engineering into cancer treatment represents a groundbreaking advancement in bioengineering, offering new avenues for targeted and personalized therapy.
This Special Issue of Bioengineering explores the latest innovations in engineering stem cells for cancer treatment and microbial infection. It covers diverse stem cell types, including embryonic, induced pluripotent, adult mesenchymal, and cancer stem cells, each with distinct advantages and challenges. Advanced genetic engineering techniques like CRISPR/Cas9 are revolutionizing the enhancement of stem cell functionalities for therapeutic purposes.
This issue highlights innovative modalities such as stem cell-mediated delivery of therapeutic agents, immune-modulating strategies, and the potential of stem cells to combat microbial infections alongside cancer. Advanced genetic engineering techniques like CRISPR/Cas9 are revolutionizing the enhancement of stem cell functionalities for therapeutic purposes. This issue highlights innovative modalities such as stem cell-mediated delivery of therapeutic agents, immune-modulating strategies, and the potential of stem cells to combat microbial infections alongside cancer. Notably, during radiation treatment, the risk of cancer necrosis can lead to microbial infections, creating additional complexities in patient care. The interactions between engineered stem cells, the tumor microenvironment, and microbial pathogens are explored, offering insights into mechanisms of action and the potential for tumor eradication and infection control.
By addressing both cancer and microbial challenges, this Special Issue aims to foster collaboration and inspire further innovation, serving as a valuable resource for researchers, clinicians, and bioengineers dedicated to advancing therapy through cutting-edge science and technology, ultimately enhancing patient outcomes.
Dr. Rishi Man Chugh
Dr. Rajnikant Sharma
Guest Editors
Manuscript Submission Information
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Keywords
- stem cell engineering
- cancer therapy
- tumor microenvironment
- immunotherapy
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