Visions of the Hereafter: Consequences of Inflammation for Pathogen and Host
A special issue of Biology (ISSN 2079-7737).
Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 578
Special Issue Editors
Interests: immunology; immunodeficiency; vaccination; pneumococcal pneumonia; SARS-CoV-2
Special Issues, Collections and Topics in MDPI journals
Interests: inflammatory processes in acute lung injury; asthma and chronic obstructive pulmonary disease (COPD); eosinophils and mast cells
Special Issue Information
Dear Colleagues,
Upon infection of the (human) host, the invading micro-organism will initially expand and proliferate. An immunocompetent host will generate an innate as well as an acquired, specific response, ultimately leading to the elimination of the micro-organism. A (theoretical) digital outcome is that either the host will die or the micro-organism will. In real life, many intermediate situations will result. For further improvement of preventive and therapeutic measures of infectious diseases, it is important to have a more complete understanding (a vision) of both microbial pathogenesis as well as host immune defenses and the ultimate outcome (the hereafter).
Visions of the Hereafter is a painting by Jheronimus Bosch, and it consists of four different panels, two of them visualizing heaven and two of them hell. Survivors from infection are depicted as being in heaven, and the panels on hell give a vivid picture of the fate of the destructive forces initiated by the inflammasome and the killing the microorganism.
In this Special Issue, contributors are encouraged to address the biological and clinical aspects of infection and inflammation, focusing on the outcome for the host as well as the pathogen. The host may be human, or any other representatives of the animal or plant kingdom. The Special Issue welcomes original research papers as well as reviews and opinion papers. A special clinical case can also be included. The Special Issue thus will provide a vision of the processes taking place during an infection, and information on how it is handled by the host, including the resolution of the infection and thereafter.
Prof. Dr. Ger Rijkers
Dr. Frans van Overveld
Dr. Samantha Samantha Scharringa
Dr. Stijn Rietkerken
Guest Editors
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Keywords
- infection
- inflammation
- immunity
- phagocytosis
- pathogenesis
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