Immunosenescence and Its Modification by Interventions
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Immunology".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 123
Special Issue Editors
Interests: immunosenescence; ageing; cancer
Special Issues, Collections and Topics in MDPI journals
Interests: immunosenescence; ageing; senolytics; T-cells but not B-cells
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Immunosenescence, the age-related decline in immune function, is a critical factor in the increased susceptibility to infections, reduced vaccine efficacy, and the development of age-related diseases in older adults. This Special Issue, "Immunosenescence and Its Modification by Interventions", aims to explore the latest advances in understanding the mechanisms of immunosenescence and the innovative approaches to mitigate its effects.
The Issue will cover a range of topics, including the cellular and molecular basis of immunosenescence, its impact on innate and adaptive immunity, and its role in age-related diseases. We will focus on cutting-edge interventions, such as novel vaccination strategies, nutritional interventions, exercise regimens, and emerging pharmacological approaches, which have been designed to modify or reverse the aspects of immunosenescence.
Contributors will present original research, reviews, and other article types that shed light on the complex interplay between aging and the immune system. The Special Issue will also address the challenges and opportunities in translating basic research findings into clinical applications for improving immune function in the elderly.
By bringing together diverse perspectives from immunology, gerontology, and related fields, this Special Issue aims to stimulate new research directions and foster interdisciplinary collaborations. Ultimately, our goal is to advance our understanding of immunosenescence and pave the way for innovative interventions that can enhance the quality of life for ageing populations.
Dr. Andreas Meryk
Dr. Luca Pangrazzi
Guest Editors
Manuscript Submission Information
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Keywords
- immunosenescence
- aging immune system
- inflammaging
- vaccine efficacy in elderly
- nutritional immunomodulation
- exercise and immunity
- senolytic therapies
- T-cell exhaustion
- thymic rejuvenation
- age-related diseases
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