Potential Theranostics of Cancer Stem Cells, Circulating Tumor Cells (Ctc), and Tumor-Derived Exosomes (EVs) Application in Lung Cancer

A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Cancer Biology".

Deadline for manuscript submissions: closed (30 September 2022) | Viewed by 505

Special Issue Editors


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Guest Editor
Division of Thoracic Surgery, Department of Thoracic Diseases, G.B. Morgagni - L. Pierantoni University Hospital of Forlì, 47121 Forlì (FO), Italy
Interests: lung cancer; cancer stem cells; lung tumor microenvironment; miRNAs exosomes; circulating tumor cells (CTC); tumor-derived exosomes (EVs)
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Guest Editor
German Cancer Research Center (DKFZ), Hoppe Children’s Cancer Center (KiTZ), University of Heidelberg, D - 69120 Heidelberg, Germany
Interests: host-tumor interactions; biomarkers; familial cancers; risk factors; germline mutations; tumor invasion front; golorectal cancer; liver metastasis; leukemia

Special Issue Information

Dear Colleagues,

Lung cancer is one of the most common cancers in the world. In 2018, there were over 2 million new cases of lung cancer, and over 1.7 million deaths were attributed to lung cancer. In addition to traditional treatments, targeted therapy has emerged as an important means of disease management for patients with non-small cell lung cancer (NSCLC). In particular, an improvement in NSCLC prognosis has been driven by immunotherapy alone or in combination with chemotherapy in both early and advanced stages, although a fraction of patients are still not responding, with relevant issues in metastatic and, more recently, in early adjuvant settings. In this scenario, cancer stem cells (CSCs), circulating tumor cells (CTCs), and tumor-derived exosomes (EVs) seem to have a central role in tumor development, cancer dissemination, and metastasis and in the resistance to commonly used medical treatments.

This Special Issue is set on the potential theranostics of these subpopulations of cells as future perspectives for more tailored treatments against cancer.

Dr. Beatrice Aramini
Dr. Obul Reddy Bandapalli
Guest Editors

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Keywords

  • cancer stem cells
  • tumor exosomes
  • lung cancer
  • circulating tumor cells
  • theranostics

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