Pathophysiology and Treatment of Atopic Dermatitis and Psoriasis, 2nd Edition
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 1780
Special Issue Editor
Interests: atopic dermatitis; psoriasis; transcriptome
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In the past few decades, research on atopic dermatitis and psoriasis has been very active. As a result, researchers have found that many biological and small-molecule drugs that target these two diseases are under development or are actually being prescribed to patients in clinical settings. However, more molecular, immunological, and neurological mechanisms and clinical studies are needed for precise medical treatment according to the patient's endotype and phenotype for each biomarker.
Atopic dermatitis and psoriasis are typical chronic inflammatory skin diseases. These were thought to be very different diseases caused by Th2 and Th1 immunological bias, respectively. However, many studies have revealed that the Th17/Th22 pathway in these two diseases has a common influence on disease initiation and chronicity. In addition to immunological abnormalities, atopic dermatitis and psoriasis have shared pathophysiology, such as abnormal skin barrier function, pruritus, genetic mutations, environmental influences, and neurophysiological abnormalities. Therefore, interesting results are often obtained when comparing these two diseases.
In this section, we welcome all research papers on molecular biology, immunology, neurophysiology, and biomarkers of atopic dermatitis and psoriasis, or research papers comparing the pathophysiology and treatment modalities of the two diseases.
Dr. Hyeone Kim
Guest Editor
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Keywords
- atopic dermatitis
- biomarker endotypes
- mutation
- next-generation sequencing
- phenotypes
- psoriasis
- transcriptome
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