Essential Oils: Pharmacological Activities and Potential Use As Therapeutic Agents

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Drug Discovery, Development and Delivery".

Deadline for manuscript submissions: closed (31 July 2024) | Viewed by 1965

Special Issue Editors


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Guest Editor
College of Medicine, Federal University of the Vale do São Francisco, Paulo Afonso CEP 48607-190, BA, Brazil
Interests: new drugs for the treatment of pain; inflammation; seizures

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Guest Editor
Departament of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa 58051-970, Paraíba, Brazil
Interests: drug delivery; medicinal chemistry; natural products

Special Issue Information

Dear Colleagues,

Nature is an important source of bioactive products that can be used to benefit human health. The classes of natural products biosynthesized in living organisms have commonly been investigated in several experimental models aiming to discover new drug candidates. In this context, essential oils and their chemical constituents prove to be promising compounds in biological and pharmacological tests as well as in clinical studies. There are a large number of scientific reports concerning their therapeutic potential, such as their anti-anxiety, antidepressant, anticonvulsant, anti-diabetic, and anti-ulcer properties. Now, the importance of these metabolites is being highlighted in the search for new drugs. Therefore, the purpose of this  Special Issue is to discuss the contribution of essential oils and their constituents in the discovery of new bioactive chemical agents with potential application in prevention treatments and pharmacotherapeutic approaches against pathologies. The establishment of possible mechanisms of action at the molecular, cellular, and animal levels, and the correlation of the chemical composition of these oils and their biological properties is recommended.

Dr. Diogo Vilar Da Fonsêca
Prof. Dr. Damião Pergentino De Sousa
Guest Editors

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Keywords

  • flavors
  • aroma
  • inhalation
  • biological activity
  • diabetes
  • anxiety
  • depression
  • epilepsy
  • ulcers
  • cancer

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Published Papers (1 paper)

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Review

34 pages, 3331 KiB  
Review
Essential Oils: Chemistry and Pharmacological Activities—Part II
by Damião Pergentino de Sousa, Francisco de Assis Oliveira, Daniel Dias Rufino Arcanjo, Diogo Vilar da Fonsêca, Allana Brunna S. Duarte, Celma de Oliveira Barbosa, Thomas Prates Ong and Timothy John Brocksom
Biomedicines 2024, 12(6), 1185; https://doi.org/10.3390/biomedicines12061185 - 27 May 2024
Viewed by 1642
Abstract
The importance of essential oils and their components in the industrial sector is attributed to their chemical characteristics and their application in the development of products in the areas of cosmetology, food, and pharmaceuticals. However, the pharmacological properties of this class of natural [...] Read more.
The importance of essential oils and their components in the industrial sector is attributed to their chemical characteristics and their application in the development of products in the areas of cosmetology, food, and pharmaceuticals. However, the pharmacological properties of this class of natural products have been extensively investigated and indicate their applicability for obtaining new drugs. Therefore, this review discusses the use of these oils as starting materials to synthesize more complex molecules and products with greater commercial value and clinic potential. Furthermore, the antiulcer, cardiovascular, and antidiabetic mechanisms of action are discussed. The main mechanistic aspects of the chemopreventive properties of oils against cancer are also presented. The data highlight essential oils and their derivatives as a strategic chemical group in the search for effective therapeutic agents against various diseases. Full article
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