The Role of Epithelial Cells in Airway Diseases
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 5238
Special Issue Editors
Interests: airway diseases; epithelial cells; cell models; biomarkers; inflammation; oxidative stress
Interests: airway diseases; epithelial cells; cell models; biomarkers; inflammation; oxidative stress
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The airway epithelium is a barrier between the environment and lung. It is a dynamic tissue that undergoes slow but constant renewal. It is the first line of defense against environmental stimuli such as cigarette smoke, allergens, microbes, and pollutants circulating in the air. The airway epithelium plays many important functions including barrier protection, fluid balance, and clearance of particulate, and contributes to both innate and adaptive immune function in the lower respiratory tract, mucus and surfactant production, and repair following injury. It contributes to both innate and adaptive immune functions in the lower respiratory tract.
Barrier dysfunction might facilitate the entrance of foreign substances, initiating and facilitating the onset of lung disease, and increasing susceptibility to respiratory infections, thereby increasing the risk of exacerbations and triggering further inflammation. All of this can induce the onset of many respiratory diseases such as COPD, asthma, fibrosis, cancer, and other disorders.
The aim of this Special issue is to examine pathophysiological processes and their related mechanisms in epithelial cells and/or to identify new and innovative therapeutic target for airway diseases.
Dr. Giusy Daniela Albano
Dr. Mirella Profita
Guest Editors
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Keywords
- airway diseases
- epithelial cells
- cell models
- biomarkers
- epithelial dysfunction
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