Recent Advances in Anti-tumor Metal Complexes and Drug Delivery Systems
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 2846
Special Issue Editors
Interests: antioxidants and oxidative stress in biological systems; modulators of oxidative stress; structural characterization of novel compounds, new ligands, and their transition metal complexes, with potential biological activity; the inhibitory potential of compounds towards major transport proteins
Special Issues, Collections and Topics in MDPI journals
Interests: antitumor drugs; molecular oncology; drug targeting; medicinal chemistry
Special Issues, Collections and Topics in MDPI journals
Interests: transition metal complexes; DFT; noncovalent interactions; DNA and protein binding affinity; spectroscopic characterization; antioxidants; free radicals
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Nowadays, there is an increased interest in the discovery of new drugs in order to adequately increase the survival rate of patients with various types of cancer, which is among the most prominent causes of death worldwide. To overcome all potential problems with the application of leading chemotherapeutic agents, such as platinum drugs, a wide range of naturally occurring phytochemicals, and their synthetic analogs, with anticancer potential are being explored for use in cancer therapy. Much attention has been given to transition metal complexes other than platinum, which should be more effective and less toxic than the existing ones. New, promising perspectives in this area are also associated with developing so-called “targeted drug delivery systems,” which are accomplished by labeling certain carriers with biologically active molecules or receptors specifically attached to targeted cells or tissues.
This Special Issue aims to present the research in the field of the design, synthesis, structural characterization, in silico numerical simulations, and biological activity evaluation of new tumor-selective compounds and their transition metal complexes, as well as their immobilization into drug delivery systems that can provide a therapeutic dose of new compounds to different cancer cells.
We welcome original research papers and reviews, dealing with novel naturally occurring phytochemicals or synthetic analogs, their transition metal complexes, and drug delivery systems with possible applications in anticancer therapy.
Prof. Dr. Jasmina Dimitrić Marković
Prof. Dr. Goran Kaluđerović
Dr. Dušan Dimić
Guest Editors
Manuscript Submission Information
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Keywords
- transition metal complexes
- synthesis
- structural characterization
- biological activity
- in silico methods
- drug delivery
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