Gene Therapy for Neurodegenerative Diseases
A special issue of Brain Sciences (ISSN 2076-3425).
Deadline for manuscript submissions: closed (15 January 2020) | Viewed by 15661
Special Issue Editor
Interests: neurological, neuromuscular and neurodegenerative diseases; gene therapy; AAV; in vitro modeling; lysosomal storage disorders
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurodegenerative disorders are a devastating burden for patients and their families. Many of these diseases progress rapidly, thereby robbing the patients of key functions including cognition, vision, hearing, and movement. There is an urgent need for the development of therapeutics to slow down or halt the progression of neurodegeneration. Gene therapy approaches using adeno-associated viral vectors (AAVs) are emerging as a promising strategy to target the nervous system and hold the potential for long-lasting benefit with only a single treatment. Many innovative strategies targeting either underlying mutations that cause neurodegeneration or interfering with pathways involved in disease progression are currently under development.
This Special Issue is dedicated to gene therapy approaches for neurodegenerative diseases. It will cover research articles on therapeutic gene therapy strategies for various disorders affecting the nervous and neuromuscular systems. Articles that describe the development of new methods or compare different viral vector systems (AAVs or other viral vectors) for nervous system use are also welcome. Comprehensive reviews providing an overview over gene therapy studies for neurodegenerative disorders or on AAV gene therapy vectors and their targeting efficiency in the nervous system will also be included.
Dr. Kathrin Meyer
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neurodegenerative disorders
- gene therapy
- adeno-associated viral vectors (AAV)
- neuromuscular disorders
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
