Tremor Mechanisms from a Network Perspective
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Systems Neuroscience".
Deadline for manuscript submissions: closed (10 October 2021) | Viewed by 373
Special Issue Editor
Special Issue Information
Dear Colleagues,
Tremor, the most common movement disorder, is defined as a rhythmic shaking of a body part by rhythmic oscillations of agonist and antagonist muscles. Its incidence and prevalence increase with aging. Tremor can be classified as rest tremor or action tremor. The most prevalent pathologic tremor is essential tremor (ET). One major symptom of Parkinson’s disease is action tremor. Both rest tremor and action tremor cause functional disability and social inconvenience, severely affecting the quality of daily life.
Despite its high prevalence and disabling effects, pharmacological intervention only helps about 50% of patients with ET, and nearly one out of three patients stop taking their medications. The development of new therapies has been hampered by a lack of knowledge about tremor pathophysiology. Therefore, it is important and necessary to understand the underlying pathophysiological mechanisms in each form of tremor.
We invite original contributions on a wide range of topics that promote our biological and systemic understanding of tremor physiology and pathology. While this collection is primarily focused on tremor mechanisms, it welcomes experimental and clinical studies that validate and test tremor therapy based on systemic modification approaches, including deep-brain stimulation, focused ultrasound stimulation, other neuromodulation treatment options, drug injection to a specific brain region, etc.
Dr. Su-Youne Chang
Guest Editor
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Keywords
- tremor
- essential tremor
- Parkinsonian tremor
- rest tremor
- action tremor
- neuromodulation
- neural network
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