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Cancers
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Study on Epidemiology of Childhood Cancer
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Study on Epidemiology of Childhood Cancer

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Epidemiology and Prevention".

Deadline for manuscript submissions: 15 March 2025 | Viewed by 2879

Special Issue Editors

Dr. Francesco Giusti

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Guest Editor
Umbria Population Cancer Registry, 06100 Perugia, Italy
Interests: cancer epidemiology and registration; healthcare systems; cancer treatment data; cancer data quality
Special Issues, Collections and Topics in MDPI journals
Dr. Carmen Martos

E-Mail
Guest Editor
Foundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO), Av. Catalunya, 21, 46020 Valencia, Spain
Interests: cancer epidemiology and registration; childhood cancer epidemiology; rare cancer epidemiology; cancer data quality
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Although cancer is rare in children and despite improved survival rates, it remains a significant cause of childhood death. Obtaining knowledge on the childhood cancer burden (incidence, mortality, prevalence and survival) in the population, its time trends, and its geographical distribution is an important starting point for cancer control. Population-based cancer registries play an essential role in measuring the childhood cancer burden. Nevertheless, factors underlying the time trend and geographic variation in childhood cancers are largely unknown. This Special Issue attempts to highlight this relevant endpoint with the aim of increasing the awareness of childhood cancer epidemiology to support the cancer control programs. We hope to include articles from population-based cancer registries, including data on the stage and treatment, research groups investigating childhood cancer risk factors, inequalities, and late effects occurring in childhood cancer survivors, as well as articles from patient and family perspectives.

Dr. Francesco Giusti
Dr. Carmen Martos
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • childhood cancer
  • epidemiology
  • childhood cancer registries
  • incidence
  • prevalence
  • mortality
  • survival
  • time trends
  • special analysis
  • environmental factors
  • perinatal factors
  • inequalities

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Published Papers (1 paper)

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22 pages, 763 KiB  
Systematic Review
Chemotherapy and Radiotherapy Long-Term Adverse Effects on Oral Health of Childhood Cancer Survivors: A Systematic Review and Meta-Analysis
by Joana Pombo Lopes, Inês Rodrigues, Vanessa Machado, João Botelho and Luísa Bandeira Lopes
Cancers 2024, 16(1), 110; https://doi.org/10.3390/cancers16010110 - 25 Dec 2023
Cited by 3 | Viewed by 2292
Abstract
The survival rate for pediatric cancer has increased over the past few decades, short- and long-term complications have been detected and studied, and oral complications have emerged as an important topic of research. Here, we aimed to highlight the importance of oral manifestations [...] Read more.
The survival rate for pediatric cancer has increased over the past few decades, short- and long-term complications have been detected and studied, and oral complications have emerged as an important topic of research. Here, we aimed to highlight the importance of oral manifestations that may only become apparent years or even decades after cancer treatment. This systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis. We searched articles using PubMed via the MEDLINE, Web of Science, and LILACS databases until October 2023. Overall, 35 observational studies were included, and the results estimated a pooled prevalence of the following dental anomalies: discoloration, 53%; crown-root malformations and agenesis, 36%; enamel hypoplasia, 32%; root development alterations, 29%; unerupted teeth, 24%; microdontia, 16%; hypodontia, 13%; and macrodontia, 7%. Most childhood cancer survivors have at least one dental sequela. Childhood cancer survivors presented a higher risk of having dental alterations than control counterparts. Additional analyses reveal possible sex-based differences that should be explored in future studies. These results collectively highlight the importance of oral healthcare and the prevention of disease in childhood cancer survivors. Full article
(This article belongs to the Special Issue Study on Epidemiology of Childhood Cancer)
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