Therapeutic Mechanism of Nervous System Inflammation—Second Edition
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 30 April 2025 | Viewed by 53
Special Issue Editors
Interests: inflammation; microglia; astrocytes; neurodegeneration; Parkinson's disease; neuroinflammation; immune system; brain; inflammatory bowel diseases
Special Issues, Collections and Topics in MDPI journals
Interests: neuroinflammation; signaling; bioactive compounds; evolutionary computational study
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neuroinflammation is a process involved in various inflammatory cascades in nervous tissues that can result in persistent and chronic apoptotic neuronal cell death, triggering various degenerative disorders of the central nervous system, including neuroinflammatory and neurodegenerative diseases.
Although neuroinflammation is a natural defense mechanism against a variety of pathologic insults within the central nervous system (CNS), excessive inflammatory responses can be harmful. To contain and repair local tissue damage, an immediate anti-inflammatory response is required. CNS-resident cells, such as microglia and astrocytes, along with peripheral immune cells, orchestrate a series of events aimed at functional restoration. If the acute inflammatory event is not resolved, it turns toxic, resulting in progressive CNS degeneration. As a result, the cellular, molecular, and biochemical processes that control inflammation must coexist with the intrinsic CNS repair mechanisms that influence tissue healing.
A better understanding of the inflammatory processes that occur prior to or during CNS damage, as well as the subsequent cascades of inflammatory reactions, could lead to the development of novel treatments.
The goal of this Special Issue is to highlight aspects that could potentially contribute as therapeutic interventions to help resolve CNS inflammation, promote tissue repair, and enable functional recovery after acute injury and infection. Cellular and molecular mechanisms, as well as potential therapeutic targets for inflammatory disorders of the nervous system, will be investigated.
Prof. Dr. Maria Anttonietta Panaro
Dr. Antonia Cianciulli
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neuroinflammation
- neurodegeneration
- therapy
- drug target
- cell signaling
- cells of nervous system
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
Related Special Issue
- Therapeutic Mechanism of Nervous System Inflammation in Cells (5 articles)
