Molecular and Cellular Mechanisms Underlying Meiotic Divisions

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Reproductive Cells and Development".

Deadline for manuscript submissions: closed (15 April 2024) | Viewed by 2863

Special Issue Editors


E-Mail Website
Guest Editor
Developmental Biology Laboratory, Institute of Biology Paris-Seine, Sorbonne University, CNRS, Paris, France
Interests: oocyte meiotic divisions in Xenopus; signal transduction; kinases and phosphatases; biochemistry of cell division; oogenesis
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Developmental Biology Laboratory, Institute of Biology Paris-Seine, Sorbonne University, CNRS, Paris, France
Interests: Xenopus and mouse meiotic maturation; regulation of protein translation; M-phase regulation

Special Issue Information

Dear Colleagues, 

At the end of the 19th century, meiosis was first observed by Oscar Hertwig in sea urchins and Edouard Van Beneden in roundworms, and its significance in terms of reproduction and heredity was understood by August Weismann. Since then, many scientists worldwide have focused on deciphering the mechanisms underlying these two very particular cell divisions, which have played an important part in creating the diversity of life on the planet. Meiosis is a key process in sexual reproduction. The two meiotic divisions, which proceed without any intervening phase of DNA duplication, generate cells containing a haploid genome: the gametes of multicellular beings and the sex cells of unicellular eukaryotes. Subsequent fusion between haploid cells, via fertilization in multicellular organisms or mating in single-cell organisms, re-establishes diploidy and produces a cell whose genome is entirely different from those of the parental cells.

Nearly 150 years after the pioneering observations of Hertwig and Van Beneden, many questions remain open. Nevertheless, the past decade has seen great advances in understanding the many specialized and regulatory processes underlying meiotic divisions: communication and interactions between germ cells and somatic cells, induction of meiotic divisions by external factors, complex signaling cascades, finely-tuned expression of maternal information, highly specialized cell divisions, specific chromosome segregation supported by adapted cytoskeleton organization and chromatin remodeling, major restructuring of the intracellular organization, detection and repair of possible defects of these divisions, acquisition of fertilizability, and many others.

This Special Issue of Cells will present a comprehensive overview of the basic mechanisms orchestrating meiotic divisions, including chapters on diverse model organisms that offer an evolutionary perspective to meiosis. Based on the contributions of world-leading experts, this Special Issue will be an essential reference for students, researchers, and physicians in the exciting field of research on this fascinating cell process.

Dr. Catherine Jessus
Dr. Enrico Maria Daldello
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • meiotic division
  • meiotic spindle
  • meiotic maturation
  • oocyte
  • oogenesis
  • spermatozoid
  • spermatogenesis
  • gamete
  • egg
  • fertilization
  • mating
  • oocyte to embryo transition
  • haploidy
  • aneuploidy
  • cell division control
  • cell division checkpoints
  • chromatin remodeling
  • regulation of protein translation
  • regulation of maternal mRNAs
  • model organisms

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

14 pages, 2739 KiB  
Review
The Importance of the Position of the Nucleus in Drosophila Oocyte Development
by Jean-Antoine Lepesant, Fanny Roland-Gosselin, Clémentine Guillemet, Fred Bernard and Antoine Guichet
Cells 2024, 13(2), 201; https://doi.org/10.3390/cells13020201 - 22 Jan 2024
Viewed by 2310
Abstract
Oogenesis is a developmental process leading to the formation of an oocyte, a haploid gamete, which upon fertilisation and sperm entry allows the male and the female pronuclei to fuse and give rise to a zygote. In addition to forming a haploid gamete, [...] Read more.
Oogenesis is a developmental process leading to the formation of an oocyte, a haploid gamete, which upon fertilisation and sperm entry allows the male and the female pronuclei to fuse and give rise to a zygote. In addition to forming a haploid gamete, oogenesis builds up a store of proteins, mRNAs, and organelles in the oocyte needed for the development of the future embryo. In several species, such as Drosophila, the polarity axes determinants of the future embryo must be asymmetrically distributed prior to fertilisation. In the Drosophila oocyte, the correct positioning of the nucleus is essential for establishing the dorsoventral polarity axis of the future embryo and allowing the meiotic spindles to be positioned in close vicinity to the unique sperm entry point into the oocyte. Full article
(This article belongs to the Special Issue Molecular and Cellular Mechanisms Underlying Meiotic Divisions)
Show Figures

Figure 1

Back to TopTop