State of the Art and Future Prospects in Stem Cell Transplantation
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Stem Cells".
Deadline for manuscript submissions: 30 April 2025 | Viewed by 3681
Special Issue Editor
Interests: bone marrow transplantation; graft versus host disease; complications after stem cell transplantation; reduced intensity stem cell transplantation; HLA-mismatch stem cell transplantation; graft engineering; cell therapy; and gene therapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Hematopoietic Stem Cell Transplantation (HSCT) has emerged as a pivotal tool against hematological malignancies. This Special Issue of "Cells" illuminates state-of-the-art advancements in HSCT, focusing on transformative strides in treating leukemia, lymphoma, and myeloma. Since the inception of allogeneic stem cell transplantation in the mid-20th century, the field has seen remarkable progress. The shift from conventional myeloablative regimens to prevalent reduced-intensity regimens signifies this evolution. The donor landscape has also broadened with cord blood transplantation and the innovative haploidentical HSCT using PTCy. A significant milestone is the recent incorporation of the Minimal Residual Disease (MRD) strategy, making HSCT decisions more scientific and precise. While we celebrate these advancements, challenges like post-transplant relapse, GVHD, and optimal donor selection remain. This Special Issue provides a comprehensive snapshot of the current landscape, emphasizing groundbreaking research and the evolving paradigms in stem cell transplantation for hematological malignancies. As readers explore these articles, from seasoned experts to newcomers, they are invited to discover the innovations shaping the future of hematologic oncology.
Prof. Dr. Shin Mineishi
Guest Editor
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Keywords
- hematopoietic stem cell transplantation
- conditioning
- graft-versus-host disease
- minimal residual disease
- HSCT
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Planned Papers
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Significance of Measurable Residual Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia
Authors: Margery Gang, Megan Othus, Roland B. Walter
Affiliation: Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA