Cellular Plasticity in Ageing
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Aging".
Deadline for manuscript submissions: closed (20 September 2022) | Viewed by 3104
Special Issue Editor
Interests: cellular senescence; in vivo reprogramming; cellular plasticity; tissue regeneration; cancer; ageing
Special Issue Information
Dear Colleagues,
Ageing is characterized by gradual functional decline and is associated with a dramatic increase in the risk of many diseases. Moreover, it has been recognized that ageing may be the underlying driving force behind many disorders. Cellular plasticity is the ability of a cell to acquire a new identity and adopt an alternative fate. Breakthroughs in the cellular reprogramming field have revealed that terminal differentiated cells can be experimentally induced to change their identities, highlighting the remarkable plasticity of differentiated cells both in vitro and in vivo and the exciting implications for regenerative medicine. Moreover, recent studies have demonstrated that certain somatic cells can acquire plasticity under physiological and pathological conditions, contributing significantly to tissue repair and disease development, especially tumorigenesis.
This Special Issue is focused on cellular plasticity in ageing and seeks original research and review articles with a focus on:
- Mechanisms for cellular plasticity regulation.
- The impact of ageing on cellular plasticity in the context of tissue regeneration and cancer.
- How to modulate plasticity for rejuvenation on the cellular, tissue, and organism level.
Dr. Han Li
Guest Editor
Manuscript Submission Information
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Keywords
- ageing
- cellular plasticity
- stem cell
- tissue regeneration
- cancer
- rejuvenation
- reprogramming
- cellular senescence
- regenerative medicine
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