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Organic Chemistry Research in Italy
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Organic Chemistry Research in Italy

A special issue of Chemistry (ISSN 2624-8549). This special issue belongs to the section "Molecular Organics".

Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 4742

Special Issue Editor

Dr. Angelo Frongia

E-Mail Website
Guest Editor
Dipartimento di Scienze Chimiche e Geologiche, Università degli Studi di Cagliari, Complesso Universitario di Monserrato, S.S. 554, Bivio per Sestu, I-09042 Monserrato, CA, Italy
Interests: development of new synthetic methods based on transformation of strained organic compounds; synthesis and exploitation of small ring compounds; design and preparation of highly functionalized heterocycle and aminoacid-inspired molecular scaffolds of biological and therapeutic interest; asymmetric synthesis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue of Chemistry regarding Italian research will publish reviews/perspectives on all fields of organic chemistry and applied organic chemistry, as well as research articles on hot topics. The topics may embrace new synthetic methods, bio-organic chemistry, organo-metallic chemistry, heteroatom chemistry, asymmetric syntheses, heterocyclic chemistry, carbocycles, macrocycles, natural product chemistry, green chemistry, organocatalysis, biocatalysis, transition metal catalysis, heterogeneous catalysis, mechanochemistry, click reactions, microwave chemistry, ionic liquids, flow chemistry, supramolecular chemistry, photochemistry, suitable aspects of medicinal chemistry and polymer chemistry as well as organic optoelectronic materials. Theoretical aspects, including mechanisms, are also within the scope of this Special Issue.

Dr. Angelo Frongia
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemistry is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • organic chemistry
  • bio-organic chemistry
  • organometallic chemistry
  • new synthetic methods
  • macromolecular chemistry
  • carbocycles
  • heterocycles
  • asymmetric syntheses
  • organocatalysis
  • biocatalysis
  • transition metal catalysis
  • heterogeneous catalysis
  • natural product chemistry
  • green chemistry
  • mechanochemistry
  • ionic liquids
  • flow chemistry
  • microwave chemistry
  • photochemistry
  • organic optoelectronic materials
  • supramolecular chemistry

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Related Special Issue

Published Papers (2 papers)

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Research

14 pages, 1615 KiB  
Article
Synthesis and Characterization of Abasic β-Diol-C-nucleosides
by Maria Moccia, Linda Piras, Gea Bellini, Michele Saviano and Mauro F. A. Adamo
Chemistry 2023, 5(2), 1343-1356; https://doi.org/10.3390/chemistry5020091 - 31 May 2023
Viewed by 1619
Abstract
Modified nucleobases are potentially useful building blocks when containing catalytically active functionalities and could be introduced in chiral tridimensional molecules such as nucleic acids, which creates the premises for the development of novel catalytic species. Herein, we describe the synthesis of a novel [...] Read more.
Modified nucleobases are potentially useful building blocks when containing catalytically active functionalities and could be introduced in chiral tridimensional molecules such as nucleic acids, which creates the premises for the development of novel catalytic species. Herein, we describe the synthesis of a novel β-C-nucleoside bearing a diol group at anomeric position, amenable as a metal ligand or organocatalyst. An abasic ligand was successfully prepared and inserted into a complementary DNA strand. Full article
(This article belongs to the Special Issue Organic Chemistry Research in Italy)
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9 pages, 9601 KiB  
Communication
A Greener Technique for Microwave-Assisted O-Silylation and Silyl Ether Deprotection of Uridine and Other Substrates
by Claudia Pasqualini, Federica Poggialini, Chiara Vagaggini, Annalaura Brai and Elena Dreassi
Chemistry 2022, 4(4), 1714-1722; https://doi.org/10.3390/chemistry4040112 - 14 Dec 2022
Viewed by 2535
Abstract
A single clean, good-yielding, environment-friendly microwave-assisted procedure for O-silylation of uridine with tert-butyldimethylsilyl chloride (TBDMSCl), 1,8-Diazabicyclo(5.4.0)undec-7-ene (DBU) and potassium nitrate as catalyst under solvent-free conditions is reported. Subsequent silyl ether deprotection is accomplished with a reusable acidic resin via microwave irradiation. [...] Read more.
A single clean, good-yielding, environment-friendly microwave-assisted procedure for O-silylation of uridine with tert-butyldimethylsilyl chloride (TBDMSCl), 1,8-Diazabicyclo(5.4.0)undec-7-ene (DBU) and potassium nitrate as catalyst under solvent-free conditions is reported. Subsequent silyl ether deprotection is accomplished with a reusable acidic resin via microwave irradiation. Both the silylation and desilylation protocols have been applied to a panel of alcohols of pharmaceutical interest. Full article
(This article belongs to the Special Issue Organic Chemistry Research in Italy)
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