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Chemosensors
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Selected Papers from the International conference on Smart Sensors (ICSS...
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Selected Papers from the International conference on Smart Sensors (ICSS 2021)

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "Electrochemical Devices and Sensors".

Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 15093

Special Issue Editors

Prof. Dr. Chi-Chang Lin

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Guest Editor
Department of Chemical and Materials Engineering, Tunghai University, Taichung 40704, Taiwan
Interests: biosensor; optical sensor; surface-enhanced Raman spectroscopy; immunosensor; biomaterial
Prof. Dr. Chia-Ming Yang

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Guest Editor
Institute of Electro-Optical Engineering, Chang Gung University, Taoyuan 333, Taiwan
Interests: chemical sensors; gas sensor; solid-state electronics; VLSI process; 2D materials; LAPS
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Chao-Sung Lai

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Guest Editor
Biomedical Engineering Research Center, Chang Gung University, Taoyuan 333, Taiwan
Interests: transistor-based sensors; metal oxides; 2D materials, nanowires; chemical sensors; gas sensors; bio-sensors
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Shih-Han Wang

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Guest Editor
Department of Chemical and Materials Engineering, National Yunlin University of Science and Technology, Yunlin, Taiwan
Interests: gas sensors; ion-selective electrodes; biosensors; electrochemical sensors; nanocomposite materials

Special Issue Information

Dear Colleagues,

ICSS 2021 is the 4th International Conference on Smart Sensors jointly hosted with The 26th symposium of Association of Chemical Sensors in Taiwan and The 24th Nano Technology and Microsystem Technology Conference. This conference offers an annual platform for international scientists, engineers and researchers to present the novel and exciting research results, ideas, developments and applications in smart sensors and materials. ICSS 2021 will be hosted by National Taiwan University in GIS NTU Convention Center from 5th to 6th July, 2021 in Taipei, Taiwan. The themes of this conference cover fields for chemical sensors, including sensing material, processing and fabrication, optical and acoustic sensors, biosensors for in vitro diagnoses, wearable and in vivo medical microsystem, sensors systems, microfluidics technologies, RF MEMS and resonators, actuators and microsystem. Original high-quality papers related to these themes are welcomed, including theories, design, modeling, simulation, reliability, fabrication, integration and applications in chemical sensors filed. All accepted abstracts will be published in the conference proceedings. Selected papers will be recommended to a Special Issue “Selected Papers from 4st ICSS 2021” of the conference proceedings papers.

Prof. Dr. Chi-Chang Lin
Prof. Dr. Chia-Ming Yang
Prof. Dr. Chao-Sung Lai
Prof. Dr. Shih-Han Wang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chemical sensors
  • nanomaterial
  • sensing material
  • optical sensor
  • process and fabrication
  • semiconductor-based sensor
  • metal-oxide based sensor
  • gas sensor
  • biosensors
  • microfluidics

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Published Papers (5 papers)

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Research

18 pages, 6392 KiB  
Article
Advanced Sensing of Antibiotics with Sr@Se Flower-Like Structure on Phosphorus-Doped g-C3N4 Composite: Application towards Detection of Chloramphenicol in Food Samples
by Sanjay Ballur Prasanna, Gagan Kumar Sakaleshpur Kumar, Sandeep Shadakshari, Santhosh Arehalli Shivamurthy, Karthik Chimatahalli Shanthakumar, Bhari Mallanna Nagaraja and Ren-Jei Chung
Chemosensors 2022, 10(10), 425; https://doi.org/10.3390/chemosensors10100425 - 17 Oct 2022
Cited by 8 | Viewed by 2023
Abstract
In this article, we developed specific sensing of chloramphenicol (CAP) using strontium selenium nanoflower-adorned phosphorus-doped graphitic carbon nitride (Sr@Se/PGCN) nanocomposite. The synthesized Sr@Se/PGCN nanocomposite was characterized using spectrophotometric techniques. Electrochemical Impedance Spectroscopy (EIS), Cyclic Voltammetry (CV), and Differential Pulse Voltammetry (DPV) were used [...] Read more.
In this article, we developed specific sensing of chloramphenicol (CAP) using strontium selenium nanoflower-adorned phosphorus-doped graphitic carbon nitride (Sr@Se/PGCN) nanocomposite. The synthesized Sr@Se/PGCN nanocomposite was characterized using spectrophotometric techniques. Electrochemical Impedance Spectroscopy (EIS), Cyclic Voltammetry (CV), and Differential Pulse Voltammetry (DPV) were used to examine the electrochemical performance of Sr@Se/PGCN nanocomposite. The Sr@Se/PGCN composite shows excellent performance with a linear range of 5–450 µM and an LOD of 2.7 nM. Furthermore, the present electrochemical CAP sensor exhibited high sensitivity, good stability, exceptional reproducibility, and an excellent recovery rate in real food samples. Full article
(This article belongs to the Special Issue Selected Papers from the International conference on Smart Sensors (ICSS 2021))
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13 pages, 2346 KiB  
Article
A Highly Sensitive Electrochemical Sensor for Cd2+ Detection Based on Prussian Blue-PEDOT-Loaded Laser-Scribed Graphene-Modified Glassy Carbon Electrode
by Londhe Akash Machhindra and Yi-Kuang Yen
Chemosensors 2022, 10(6), 209; https://doi.org/10.3390/chemosensors10060209 - 2 Jun 2022
Cited by 20 | Viewed by 3719
Abstract
Heavy metal ion pollution has had a serious influence on human health and the environment. Therefore, the monitoring of heavy metal ions is of great practical significance. In this work, we describe the development of an electrochemical sensor to detect cadmium (Cd2+ [...] Read more.
Heavy metal ion pollution has had a serious influence on human health and the environment. Therefore, the monitoring of heavy metal ions is of great practical significance. In this work, we describe the development of an electrochemical sensor to detect cadmium (Cd2+) using a Prussian blue (PB), poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT)-loaded laser-scribed graphene (LSG) nanocomposite-modified glassy carbon electrode (GCE). In this nanocomposite material, we successfully brought together the advantages of an extraordinarily large surface area. The accumulation of PB nanoparticles results in an efficient electrochemical sensor with high sensitivity and selectivity and fast detection ability, developed for the trace-level detection of Cd2+. Electrochemical features were explored via cyclic voltammetry (CV), whereas the stripping voltammetry behavior of modified electrodes was analyzed by utilizing differential pulse voltammetry. Compared with bare GCE, the LSG/PB-PEDOT/GCE modified electrode greatly increased the anodic stripping peak currents of Cd2+. Under the optimized conditions, the direct and facile detection of Cd2+ was achieved with a wide linear range (1 nM–10 µM) and a low LOD (0.85 nM). Full article
(This article belongs to the Special Issue Selected Papers from the International conference on Smart Sensors (ICSS 2021))
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16 pages, 9348 KiB  
Article
Detection of Single Nucleotide Polymorphism (SNP) Variation of a Gene Sequence on Membrane-Based Lateral-Flow Strips
by Jui-Chuang Wu, Jia-Cheng Yang and Yi-Jing Hsieh
Chemosensors 2022, 10(2), 59; https://doi.org/10.3390/chemosensors10020059 - 31 Jan 2022
Cited by 2 | Viewed by 2709
Abstract
This study used appropriate primers to distinguish the gene model, HLA-A31:01, on membrane-based lateral-flow (MBLF) strips from its allele, which is with an SNP. Using primers designed with a mismatch base on one or two sides next to the SNP spot was verified [...] Read more.
This study used appropriate primers to distinguish the gene model, HLA-A31:01, on membrane-based lateral-flow (MBLF) strips from its allele, which is with an SNP. Using primers designed with a mismatch base on one or two sides next to the SNP spot was verified as a good approach. In the optimal condition, the detection limits of 1~0.1 ng/μL nucleotides were in agreement with reports in the literature, and the intra- and inter-assay tests ensured the detection reproducibility of this approach with CV% of 2.5~15.9% and 1.7~14.7%, respectively. The detection specificity was also validated by the tests on the selected negative-control genes. The tests on MBLF strips in this study showed an easy, robust, reproducible, and reliable detection methodology for untrained personnel at care points with limited instrument and particularly for avoiding medications from faulty prescriptions. Full article
(This article belongs to the Special Issue Selected Papers from the International conference on Smart Sensors (ICSS 2021))
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11 pages, 2557 KiB  
Article
A Systematic Study and Potential Limitations of Proton-ELISA Platform for α-Synuclein Antigen Detection
by Chia-Ming Yang, Jia-Yuan Chang, Min-Yi Chen and Chao-Sung Lai
Chemosensors 2022, 10(1), 5; https://doi.org/10.3390/chemosensors10010005 - 24 Dec 2021
Cited by 3 | Viewed by 2800
Abstract
To evaluate point-of-care testing (POCT) for the potential early detection of biomarkers of Parkinson’s disease, a systematic investigation of portable and low-cost platforms is performed based on the Proton-enzyme-linked immunosorbent assay (Proton-ELISA) methodology. The detection of the α-synuclein antigen was first presented by [...] Read more.
To evaluate point-of-care testing (POCT) for the potential early detection of biomarkers of Parkinson’s disease, a systematic investigation of portable and low-cost platforms is performed based on the Proton-enzyme-linked immunosorbent assay (Proton-ELISA) methodology. The detection of the α-synuclein antigen was first presented by biotin-relative linkers, and glucose substrate solution was first performed with a systematic experimental design to optimize the sensing results. All materials in this study are commercially available. Three different experiments with the partitional check were performed to investigate the Proton-ELISA platform, including proton catalyzed efficiency, blocking efficiency, and full Proton-ELISA procedure. The response time was selected as 15 min by the time-dependent curves of a full reaction. The limit of detection of conventional ELISA kits is 0.169 ng/mL, which is much lower than the Proton-ELISA results. The final response of the full Proton-ELISA procedure to pH changes was approximately 0.60 and 0.12 for α-synuclein antigen concentrations of 100 ng/mL and 4 ng/mL, respectively. With the partitional check, pH changes of pure glucose substrate and conjugated oxidase and interference of the nonspecific binding are 1.7 and 0.04, respectively. The lower pH changes far from the partitional check results can be concluded for the properties of glucose oxidase conjugation, including the isoelectric point and binding affinity modification by the testing environment. This preliminary guideline can be used as a lesson learnt to speed up following studies of the evaluation and optimization of other antigen detection. Therefore, Proton-ELISA can be suggested for some special applications with the help of custom-designed conjugation in the environment with less degradation or interference and a proper detection concentration range. Full article
(This article belongs to the Special Issue Selected Papers from the International conference on Smart Sensors (ICSS 2021))
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15 pages, 4936 KiB  
Article
Application of the Non-Enzymatic Glucose Sensor Combined with Microfluidic System and Calibration Readout Circuit
by Jung-Chuan Chou, Yu-Hao Huang, Po-Yu Kuo, Chih-Hsien Lai, Yu-Hsun Nien, Yung-Yu Chen, Zhi-Xuan Kang and Kun-Tse Lee
Chemosensors 2021, 9(12), 351; https://doi.org/10.3390/chemosensors9120351 - 10 Dec 2021
Cited by 2 | Viewed by 2467
Abstract
In this research, we proposed a potentiometric sensor based on copper doped zinc oxide (CZO) films to detect glucose. Silver nanowires were used to improve the sensor’s average sensitivity, and we used the low power consumption instrumentation amplifier (UGFPCIA) designed by our research [...] Read more.
In this research, we proposed a potentiometric sensor based on copper doped zinc oxide (CZO) films to detect glucose. Silver nanowires were used to improve the sensor’s average sensitivity, and we used the low power consumption instrumentation amplifier (UGFPCIA) designed by our research group to measure the sensing characteristics of the sensor. It was proved that the sensor performs better when using this system. In order to observe the stability of the sensor, we also studied the influence of two kinds of non-ideal effects on the sensor, such as the drift effect and the hysteresis effect. For this reason, we chose to combine the calibration readout circuit with the voltage-time (V-T) measurement system to optimize the measurement environment and successfully reduced the instability of the sensor. The drift rate was reduced by about 51.1%, and the hysteresis rate was reduced by 13% and 28% at different measurement cycles. In addition, the characteristics of the sensor under dynamic conditions were also investigated, and it was found that the sensor has an average sensitivity of 13.71 mV/mM and the linearity of 0.998 at a flow rate of 5.6 μL/min. Full article
(This article belongs to the Special Issue Selected Papers from the International conference on Smart Sensors (ICSS 2021))
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