Allergic Rhinitis in Childhood

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Global Pediatric Health".

Deadline for manuscript submissions: closed (15 June 2021) | Viewed by 5765

Special Issue Editor

Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, 2820 Copenhagen, Denmark
Interests: asthma; allergic rhinitis

Special Issue Information

Dear Colleagues,

For this Special Issue, Dr. Chawes invites contributions in the form of original articles and reviews to an article collection on allergic rhinitis in childhood not limited to the following themes: 1) the natural history of allergic sensitization, nonallergic and allergic rhinitis during childhood; 2) lifestyle and environmental risk factors for the development of allergic rhinitis in childhood such as air pollution, greenness, tobacco smoke exposure, indoor allergens, respiratory infections, and the microbiome; 3) the role of dietary factors as preventive measures, including breastfeeding, formula feeding, and dietary supplements such as vitamin D; 4) the role of omics for endotyping allergic rhinitis, including genetics, gene expression, epigenetics, pharmacogenomics, and metabolomics; 5) the treatment of allergic rhinitis, including immunological targets for treatment and allergen immunotherapy; and 6) treatment barriers and measures to increase adherence.

Dr. Bo Chawes
Guest Editor

Manuscript Submission Information

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Keywords

  • Allergic rhinitis
  • Natural history
  • Exposome
  • Prevention
  • Endotyping
  • Treatment
  • Adherence

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Published Papers (1 paper)

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Review

12 pages, 305 KiB  
Review
The Role of Environmental Risk Factors on the Development of Childhood Allergic Rhinitis
by Allison C. Wu, Amber Dahlin and Alberta L. Wang
Children 2021, 8(8), 708; https://doi.org/10.3390/children8080708 - 17 Aug 2021
Cited by 12 | Viewed by 5103
Abstract
Environmental factors play an important role in the development and exacerbation of allergic rhinitis (AR) in childhood. Indoor air pollution, such as house dust mites and secondhand smoke, can significantly increase the onset of AR, while pet dander may affect the exacerbation of [...] Read more.
Environmental factors play an important role in the development and exacerbation of allergic rhinitis (AR) in childhood. Indoor air pollution, such as house dust mites and secondhand smoke, can significantly increase the onset of AR, while pet dander may affect the exacerbation of AR symptoms in children. Furthermore, traffic related air pollution and pollen are outdoor air pollutants that can affect immune competency and airway responsiveness, increasing the risk of AR in children. Climate change has increased AR in children, as growth patterns of allergenic species have changed, resulting in longer pollen seasons. More extreme and frequent weather events also contribute to the deterioration of indoor air quality due to climate change. Additionally, viruses provoke respiratory tract infections, worsening the symptoms of AR, while viral infections alter the immune system. Although viruses and pollution influence development and exacerbation of AR, a variety of treatment and prevention options are available for AR patients. The protective influence of vegetation (greenness) is heavily associated with air pollution mitigation, relieving AR exacerbations, while the use of air filters can reduce allergic triggers. Oral antihistamines and intranasal corticosteroids are common pharmacotherapy for AR symptoms. In this review, we discuss the environmental risk factors for AR and summarize treatment strategies for preventing and managing AR in children. Full article
(This article belongs to the Special Issue Allergic Rhinitis in Childhood)
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