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Children
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Skeletal Muscle Development from Infancy to Adolescence
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Skeletal Muscle Development from Infancy to Adolescence

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Global Pediatric Health".

Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 9842

Special Issue Editor

Prof. Andy Khamoui

E-Mail Website
Guest Editor
Department of Exercise Science and Health Promotion, Integrative Biology Graduate Program, Institute for Human Health and Disease Intervention, Florida Atlantic University, Boca Raton, FL, USA
Interests: skeletal muscle physiology; cancer cachexia; exercise and nutrient metabolism; mitochondrial function in health and disease

Special Issue Information

Dear Colleagues,

It is my pleasure to serve as guest editor for this Special Issue on “Skeletal Muscle Development from Infancy to Adolescence”. Skeletal muscle comprises roughly 40% of the body mass and is critical for ventilation, locomotion and metabolic health. This organ system is affected in several congenital myopathies, muscular dystrophies and neuromuscular disorders for which effective treatments are lacking. Skeletal muscle also demonstrates remarkable plasticity by adapting its structure and function to a variety of signals such as injury, disuse, physical inactivity, exercise, and nutrients. This Special Issue will explore skeletal muscle health with a focus on early life, from infancy through to adolescence. Submissions are welcome from any experimental system, including, but not limited to, cells, model organisms, and human subjects. Original research and reviews that highlight mechanisms and therapies for inherited myopathies and neuromuscular disease are especially welcome, as are submissions in the areas of pediatric exercise science, and the influence of diet and nutrients on muscle health in pediatric populations. The overall goals of this Special Issue are to increase the awareness and understanding of avenues that can promote skeletal muscle health during these critical stages of life.

Prof. Andy Khamoui
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pediatrics
  • infants
  • children
  • adolescents
  • neuromuscular disorders and diseases
  • muscular dystrophies
  • myopathies
  • muscular atrophy
  • obesity and metabolic disease
  • pediatric exercise and sports science
  • nutrition and diet
  • measurement and evaluation
  • pre-clinical and clinical research

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

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Research

5 pages, 190 KiB  
Communication
The Measurement of Strength in Children: Is the Peak Value Truly Maximal?
by Hayao Ozaki, Takashi Abe, Scott J. Dankel, Jeremy P. Loenneke, Toshiharu Natsume, Pengyu Deng and Hisashi Naito
Children 2021, 8(1), 9; https://doi.org/10.3390/children8010009 - 26 Dec 2020
Cited by 10 | Viewed by 2788
Abstract
It is unclear whether the measurement of maximum muscle strength in younger children can be performed accurately due to factors such as motivation and maturity (i.e., the ability to receive instruction). If there is a large change in a ratio between muscular strength [...] Read more.
It is unclear whether the measurement of maximum muscle strength in younger children can be performed accurately due to factors such as motivation and maturity (i.e., the ability to receive instruction). If there is a large change in a ratio between muscular strength and size from the youngest to the oldest, then this might provide some indication that the youngest may not have been able to voluntarily activate their muscles for reasons mentioned previously. The purpose of this study was to observe the ratio between handgrip strength (HGS) and forearm muscle thickness (MT) across differing ages in younger children. A total of 1133 preschool children (559 boys and 574 girls) between the ages of 4.5 and 6.5 years had MT and HGS measurements and calculated the ratio of HGS/MT (kg/cm). Linear regression was used to assess the impact of age and sex on the dependent variables of MT, HGS, and the HGS/MT ratio. The HGS/MT ratio increases moderately from age 4.5 to 6.5 in both boys and girls. However, the difference in this ratio was small between the age ranges in this sample. Our results indicate children as young as 4.5 may be accurately measured with the handgrip strength test. Full article
(This article belongs to the Special Issue Skeletal Muscle Development from Infancy to Adolescence)
17 pages, 3630 KiB  
Article
Body Posture Defects and Body Composition in School-Age Children
by Jacek Wilczyński, Magdalena Lipińska-Stańczak and Igor Wilczyński
Children 2020, 7(11), 204; https://doi.org/10.3390/children7110204 - 29 Oct 2020
Cited by 18 | Viewed by 5322
Abstract
The aim of the study was to assess the relationship between the shape of the anteriorposterior spinal curvature and body composition in schoolchildren. The study included 257 children, aged 11–12. Correct spinal curvature was established in 106 (41.08%) subjects. Other types included: decreased [...] Read more.
The aim of the study was to assess the relationship between the shape of the anteriorposterior spinal curvature and body composition in schoolchildren. The study included 257 children, aged 11–12. Correct spinal curvature was established in 106 (41.08%) subjects. Other types included: decreased kyphosis and correct lordosis—40 participants (15.50%), correct kyphosis and decreased lordosis—24 individuals (9.30%), increased kyphosis and correct lordosis—17 subjects (6.59%), correct kyphosis and increased lordosis—22 children (8.53%), decreased kyphosis and decreased lordosis—32 people (12.40%), decreased kyphois and increased lordosis—four of the examined subjects (1.55%) increased kyphosis and lordosis—13 people (5.04%). In addition, 134 (51.94%) demonstrated scoliotic posture and eight (3.10%) scoliosis. There were significant relationships between the shape of the anteriorposterior curvatures and body composition in schoolchildren. Those with a strong body build (predominance of mesomorphs) were generally characterised by the correct formation of these curvatures. In contrast, lean subjects (with the predominance of ectomorphic factors) were more likely to experience abnormalities. No correlations with body composition were observed in the group with scoliotic posture or scoliosis. Both in the prevention and correction of postural defects, one should gradually move away from one-sided, usually one-system, therapeutic effects. An approach that takes into account both somatic and neurophysiological factors seems appropriate. With the correct body composition and structure, shaping the habit of correct posture is much easier. Full article
(This article belongs to the Special Issue Skeletal Muscle Development from Infancy to Adolescence)
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