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Dentistry Journal
Special Issues
Oral Health to Global Health: Impact of Nutrition
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Oral Health to Global Health: Impact of Nutrition

A special issue of Dentistry Journal (ISSN 2304-6767).

Deadline for manuscript submissions: closed (30 September 2020) | Viewed by 46817

Special Issue Editor

Prof. Dr. Mohammed S. Razzaque

E-Mail Website
Guest Editor
Professor of Pathology, Lake Erie College of Osteopathic Medicine, 1858 West Grandview Boulevard, Erie, PA 16509, USA
Interests: nutrition; oral health; global health; aging; tumorigenesis

Special Issue Information

Dear Colleagues,

The impact of oral health on systemic diseases are well documented. Studies have shown up to 50% of heart attacks have a strong association with oral bacteria. A close link between periodontal diseases and diabetes, hypertension, neurologic disorders and autoimmune diseases are convincingly demonstrated in large cohorts. More, importantly, oral manifestations are one of the earliest clues of the evolvement of some of these prevalent systemic diseases. As the gap between various branches of medicine and dentistry is closing, a coordinated approach of maintaining optimal oral health would not only reduce commonly encountered systemic diseases, but would also significantly diminish global health burdens.

This Special Issue is intended to bring together different branches of dental, medical and nutritional specialties to share their experiences, with the aim of reducing oral health burden to improve systemic diseases and beyond. This Special Issue of welcomes the submission of original manuscripts (unpublished research works), updated reviews (of the existing literate), and brief commentaries (on emerging areas of global health concern).

Prof. Dr. Mohammed S. Razzaque
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Dentistry Journal is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Nutrition
  • Oral health
  • Global health
  • Epidemiology
  • Prevalence and incidence
  • Etiology and pathology
  • Risk factors
  • Prevention
  • Morphology
  • Diagnosis
  • Therapy
  • Periodontal treatment
  • Dental implants
  • Orthodontic treatment
  • Complications
  • Preventive health
  • Experimental models

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (5 papers)

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Research

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13 pages, 2053 KiB  
Article
Effect of Dietary Fiber on the Composition of the Murine Dental Microbiome
by Lea Sedghi, Craig Byron, Ryan Jennings, George E. Chlipala, Stefan J. Green and Laura Silo-Suh
Dent. J. 2019, 7(2), 58; https://doi.org/10.3390/dj7020058 - 1 Jun 2019
Cited by 17 | Viewed by 4486
Abstract
The oral cavity houses a diverse consortium of microorganisms, heavily influenced by host diet, that can mediate dental health and disease. While the impact of dietary carbohydrates to the dental microbiome has been well-documented, the effect of fiber as a mechanical influence on [...] Read more.
The oral cavity houses a diverse consortium of microorganisms, heavily influenced by host diet, that can mediate dental health and disease. While the impact of dietary carbohydrates to the dental microbiome has been well-documented, the effect of fiber as a mechanical influence on the dental microbiome is unexplored. We performed 16S rRNA gene analysis to investigate the response of the dental microbiome to the presence of increased fiber in terms of microbial taxonomic abundance and diversity. Dental microbial community structure was significantly different in mice fed a diet supplemented with increased fiber and/or sugar. Fiber significantly affected measures of beta diversity at the phylum and genus levels, and a strong interactive effect on alpha diversity was observed between sugar and fiber at the phylum level. The addition of fiber also induced significant variation in relative taxonomic abundance. This study demonstrates that fiber can promote significant variations in the mouse dental microbiome. Full article
(This article belongs to the Special Issue Oral Health to Global Health: Impact of Nutrition)
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12 pages, 5659 KiB  
Article
Effect of Collagen Cross-Link Deficiency on Incorporation of Grafted Bone
by Suliman Mubarak, Nagasawa Masako, Farah A. Al-Omari, Hamaya Keisuke and Uoshima Katsumi
Dent. J. 2019, 7(2), 45; https://doi.org/10.3390/dj7020045 - 1 May 2019
Cited by 1 | Viewed by 3515
Abstract
Bone matrix collagen, is one of the major contributors to bone quality. No studies have examined how bone quality affects the results of bone transplantation. Collagen cross-links (CCL) are the key factor in collagen properties. The purpose was to investigate the influences of [...] Read more.
Bone matrix collagen, is one of the major contributors to bone quality. No studies have examined how bone quality affects the results of bone transplantation. Collagen cross-links (CCL) are the key factor in collagen properties. The purpose was to investigate the influences of CCL for both grafted bone and recipient site bone on the success of bone augmentation. Four-week-old male Wister rats (n = 54) were divided into control and test groups. Control and test groups equally sub-divided into donors and recipients. An additional six rats were used to characterize bone at day zero. Test groups received 0.2% beta-aminoproperionitrile (BAPN) for 4 weeks as CCL inhibitor. Animals were further divided into donor and recipient groups. The transplanted bone chips integrated with host bone by 25% more in CCL-deficient animals compared to control. However, no difference in cortical thickness among all conditions. CCL-deficient transplanted bone did not show any extra signs of osteocyte apoptosis, while sclerostin expression was comparable to that in control. The host periosteum of CCL-deficient animals showed higher cellular activity, as well as higher bone quantity and osteoclast activity. Collagen cross-links deficiency in host bone might accelerate the incorporation of grafted bone. effect. Incorporation of the bone grafts appears to depend mainly on host condition rather than graft condition. Full article
(This article belongs to the Special Issue Oral Health to Global Health: Impact of Nutrition)
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Review

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13 pages, 2340 KiB  
Review
Dental Plaque Removal by Ultrasonic Toothbrushes
by Ilya Digel, Inna Kern, Eva Maria Geenen and Nuraly Akimbekov
Dent. J. 2020, 8(1), 28; https://doi.org/10.3390/dj8010028 - 23 Mar 2020
Cited by 23 | Viewed by 16036
Abstract
With the variety of toothbrushes on the market, the question arises, which toothbrush is best suited to maintain oral health? This thematic review focuses first on plaque formation mechanisms and then on the plaque removal effectiveness of ultrasonic toothbrushes and their potential in [...] Read more.
With the variety of toothbrushes on the market, the question arises, which toothbrush is best suited to maintain oral health? This thematic review focuses first on plaque formation mechanisms and then on the plaque removal effectiveness of ultrasonic toothbrushes and their potential in preventing oral diseases like periodontitis, gingivitis, and caries. We overviewed the physical effects that occurred during brushing and tried to address the question of whether ultrasonic toothbrushes effectively reduced the microbial burden by increasing the hydrodynamic forces. The results of published studies show that electric toothbrushes, which combine ultrasonic and sonic (or acoustic and mechanic) actions, may have the most promising effect on good oral health. Existing ultrasonic/sonic toothbrush models do not significantly differ regarding the removal of dental biofilm and the reduction of gingival inflammation compared with other electrically powered toothbrushes, whereas the manual toothbrushes show a lower effectiveness. Full article
(This article belongs to the Special Issue Oral Health to Global Health: Impact of Nutrition)
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19 pages, 290 KiB  
Review
Dental Infection and Resistance—Global Health Consequences
by Mainul Haque, Massimo Sartelli and Seraj Zohurul Haque
Dent. J. 2019, 7(1), 22; https://doi.org/10.3390/dj7010022 - 1 Mar 2019
Cited by 61 | Viewed by 16067
Abstract
Antibiotics are widely used in dental caries and another dental related issues, both for therapeutic and prophylactic reasons. Unfortunately, in recent years the use of antibiotics has been accompanied by the rapid emergence antimicrobial resistance. Dental caries and periodontal diseases are historically known [...] Read more.
Antibiotics are widely used in dental caries and another dental related issues, both for therapeutic and prophylactic reasons. Unfortunately, in recent years the use of antibiotics has been accompanied by the rapid emergence antimicrobial resistance. Dental caries and periodontal diseases are historically known as the top oral health burden in both developing and developed nations affecting around 20–50% of the population of this planet and the uppermost reason for tooth loss. Dental surgeons and family practitioners frequently prescribed antimicrobials for their patients as outpatient care. Several studies reported that antibiotics are often irrationally- and overprescribed in dental diseases which is the basis of antimicrobial resistance. The aim of this review is to evaluate the use of antibiotics in dental diseases. Almost certainly the promotion of primary oral health care (POHC) in primary health care program especially among the least and middle-income countries (LMIC) may be the answer to ensure and promote rational dental care. Full article
(This article belongs to the Special Issue Oral Health to Global Health: Impact of Nutrition)

Other

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8 pages, 573 KiB  
Perspective
Dysregulated Phosphate Metabolism, Periodontal Disease, and Cancer: Possible Global Health Implications
by Ronald B. Brown
Dent. J. 2019, 7(1), 18; https://doi.org/10.3390/dj7010018 - 11 Feb 2019
Cited by 11 | Viewed by 5772
Abstract
An association between periodontal disease and cancer has been established in recent studies, but no common etiology has been identified in the hopes of reducing the global burden of these non-communicable diseases. This perspective article hypothesizes that the determinant mediating the association of [...] Read more.
An association between periodontal disease and cancer has been established in recent studies, but no common etiology has been identified in the hopes of reducing the global burden of these non-communicable diseases. This perspective article hypothesizes that the determinant mediating the association of periodontal disease with cancer is dysregulated phosphate metabolism. Phosphate, an essential dietary micronutrient, is dysregulated in chronic kidney disease, and both cancer and periodontal disease are associated with chronic kidney disease. Reviewed evidence includes the association between phosphate toxicity and cancer development, and the association between periodontal disease and chronic kidney disease-mineral and bone disorder includes conditions such as ectopic calcification and bone resorption, which may be indirectly related to periodontal disease. Dental calculus in periodontal disease contains calcium phosphate crystals that are deposited from excess calcium and phosphate in saliva. Alveolar bone resorption may be linked systemically to release of parathyroid hormone in response to hypocalcemia induced by hyperphosphatemia. More research is needed to examine the role of dysregulated phosphate metabolism in periodontal disease. Full article
(This article belongs to the Special Issue Oral Health to Global Health: Impact of Nutrition)
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