Oral Microbiome in Human Health and Disease

A special issue of Dentistry Journal (ISSN 2304-6767).

Deadline for manuscript submissions: closed (30 November 2019) | Viewed by 4732

Special Issue Editor

Special Issue Information

Dear Colleagues,

Epidemiological studies indicated that more than 15% of the population in western countries suffer because of severe forms of periodontitis. In the light of the available knowledge to date on the pathogenetic mechanisms of such an infection, it is possible to affirm that different risk factors can influence its onset, evolution, and therapeutic possibilities. In the examination of the risk factors in the development of periodontal pathology, the effects of systemic conditions on the health of the oral cavity have been reported, as well as the influence of the periodontal pathology on the onset and on the evolution of several systemic pathologies related to certain physiological conditions. In fact, periodontitis may increase the risk of group of life-threatening conditions such as atherosclerosis, stroke, or low birth weight.
In this respect, the recognition of the relationship between oral and systemic health is growing, and is thus receiving remarkable interest in the scientific literature.

Thank you very much!

Prof. Luigi Santacroce
Guest Editor

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Keywords

  • human microbioma
  • oral microbioma
  • periodontitis
  • oral hygiene
  • dental hygiene
  • pulmonary diseases
  • diabetes
  • cancer
  • cardiovascular diseases
  • preterm birth
  • pregnancy
  • gastrointestinal conditions

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Published Papers (1 paper)

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Research

12 pages, 980 KiB  
Article
Anorexia, Oral Health and Antioxidant Salivary System: A Clinical Study on Adult Female Subjects
by Marco Mascitti, Erminia Coccia, Arianna Vignini, Luca Aquilanti, Andrea Santarelli, Eleonora Salvolini, Jacopo Sabbatinelli, Laura Mazzanti, Maurizio Procaccini and Giorgio Rappelli
Dent. J. 2019, 7(2), 60; https://doi.org/10.3390/dj7020060 - 1 Jun 2019
Cited by 5 | Viewed by 4203
Abstract
The aim of this study was to compare the oral health status and salivary antioxidant system between patients diagnosed with anorexia nervosa (AN) and healthy controls. A total of 25 female AN patients and 25 matched healthy controls were enrolled. Clinical parameters and [...] Read more.
The aim of this study was to compare the oral health status and salivary antioxidant system between patients diagnosed with anorexia nervosa (AN) and healthy controls. A total of 25 female AN patients and 25 matched healthy controls were enrolled. Clinical parameters and saliva samples were collected for each patient. Two questionnaires to investigate oral health and hygiene were administered. Superoxide Dismutase (SOD) activity and High Reactive Oxygen Species (hROS) were evaluated. Salivary concentration of SOD was significantly higher in subjects with AN compared with control group (1.010 ± 0.462 vs. 0.579 ± 0.296 U/mL; p = 0.0003). No significant differences between groups were identified for hROS (233.72 ± 88.27 vs. 199.49 ± 74.72; p = 0.15). Data from questionnaires indicated that, although most of the patients recognized the oral hygiene importance in maintaining a good oral health, more than half of them had poor oral hygiene. Altered biochemical composition of saliva in patients with AN could be interpreted as an effective defence mechanism against oxidative stress. Moreover, despite the discrepancy between clinical findings and perception of the oral health in AN population arose, the quality of life of these patients appears not to be significantly affected by their dental condition. Full article
(This article belongs to the Special Issue Oral Microbiome in Human Health and Disease)
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