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Diagnostics
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Advances in the Diagnosis and Management of Urologic Diseases
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Advances in the Diagnosis and Management of Urologic Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 1360

Special Issue Editors

Dr. Uroš Bumbaširević

E-Mail Website
Guest Editor
1. Clinic of Urology, University Clinical Center of Serbia, 11000 Belgrade, Serbia
2. Faculty of Medicine, University of Belgrade,11000 Belgrade, Serbia
Interests: testicular cancer; urologic oncology; BPH; urolithiasis
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Otas Durutovic

E-Mail Website
Guest Editor
1. Clinic of Urology, University Clinical Center of Serbia, 11000 Belgrade, Serbia
2. Faculty of Medicine, University of Belgrade,11000 Belgrade, Serbia
Interests: endourology; urolithiasis; prostate disease; andrology

Special Issue Information

Dear Colleagues,

Urology continues to serve as a prime example of ongoing innovation and advancement in the ever-changing field of medicine. There is a wide spectrum of diseases that affect the urinary system and the male genitalia, varying from benign to cancerous and harmless to incapacitating. Recent advancements in diagnostics have allowed medical practitioners to identify urological disorders with previously unprecedented accuracy. Regarding the development of treatment strategies, there has been a paradigm shift toward minimally invasive urological surgery that prioritizes patient-centered therapy and technology improvements. This Special Issue welcomes the submission of papers that could deepen our understanding of the diagnosis and treatment of urologic diseases.

Dr. Uroš Bumbaširević
Prof. Dr. Otas Durutovic
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • urologic diseases
  • diagnosis
  • management
  • urologic oncology
  • endourology
  • minimally invasive surgery
  • urolithiasis

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Published Papers (2 papers)

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Research

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12 pages, 854 KiB  
Article
Evaluation of Peri-Operative Outcomes after Prostatic Urethral Lift with Emphasis on Urodynamic Changes, Symptom Improvement and Sexual Function
by Riccardo Lombardo, Valerio Santarelli, Beatrice Turchi, Giuseppe Santoro, Alessandro Guercio, Antonio Franco, Silvia Secco, Paolo Dell’Oglio, Antonio Galfano, Alberto Olivero, Antonio Luigi Pastore, Yazan Al Salhi, Andrea Fuschi, Antonio Nacchia, Giorgia Tema, Alessandra Fegiz, Ferdinando Fusco, Riccardo Cini, Antonio Cicione, Andrea Tubaro and Cosimo De Nunzioadd Show full author list remove Hide full author list
Diagnostics 2024, 14(19), 2110; https://doi.org/10.3390/diagnostics14192110 - 24 Sep 2024
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Abstract
Background and Aims: The aim of our study is to evaluate the possible urodynamic effect of prostatic urethral lift (PUL) in patients with lower urinary tract symptoms due to benign prostatic hyperplasia. Methods: A consecutive series of patients undergoing PUL placement were [...] Read more.
Background and Aims: The aim of our study is to evaluate the possible urodynamic effect of prostatic urethral lift (PUL) in patients with lower urinary tract symptoms due to benign prostatic hyperplasia. Methods: A consecutive series of patients undergoing PUL placement were consecutively enrolled in two centers. Inclusion criteria: ≥50 years of age, benign prostatic obstruction (BPO), international prostate symptom score (IPSS) ≥ 13, prostate volume ≤ 60 mL, and no middle prostate lobe. All patients were evaluated using a detailed clinical history, a validated questionnaire, flexible cystoscopy, and pressure flow studies (PFS) at baseline. PFS were performed at 6 months to evaluate the urodynamic effect of PUL. Results: Overall, 20 patients with a median age of 63 were enrolled. At six months, statistically significant improvements in terms of median Qmax (11.5 vs. 8.5; p < 0.05) and median IPSS (16 vs. 10.5; p < 0.05) were recorded, and sexual function was maintained. All urodynamic parameters improved at 6 months, and significance was reached for all values except for PdetQmax. Finally, Schäfer’s class improved from a median of III to a median of II. More specifically, 16/20 presented an improvement in the Schäfer class, and 12/20 patients presented a BOOI < 20 at 6 months. Conclusions: PUL represents an effective treatment in patients with LUTS due to BPH and improves bladder outlet obstruction without any effect on sexual function. Full article
(This article belongs to the Special Issue Advances in the Diagnosis and Management of Urologic Diseases)
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14 pages, 16334 KiB  
Case Report
Bladder Adenocarcinoma in a Constellation of Multiple Site Malignancies: An Unusual Case and Systematic Review
by Daniel Porav-Hodade, Raul Gherasim, Andrada Loghin, Bianca Lazar, Ovidiu Simion Cotoi, Mihail-Alexandru Badea, Mártha Orsolya Katalin Ilona, Ciprian Todea-Moga, Mihai Dorin Vartolomei, Georgescu Rares, Nicolae Crisan and Ovidiu Bogdan Feciche
Diagnostics 2024, 14(22), 2510; https://doi.org/10.3390/diagnostics14222510 - 9 Nov 2024
Viewed by 593
Abstract
Background and Objectives: Multiple primary malignant tumors represent a small percentage of the total number of oncological cases and can involve either metachronous or synchronous development and represent challenges in diagnosis, staging, and treatment planning. Our purpose is to present a rare case [...] Read more.
Background and Objectives: Multiple primary malignant tumors represent a small percentage of the total number of oncological cases and can involve either metachronous or synchronous development and represent challenges in diagnosis, staging, and treatment planning. Our purpose is to present a rare case of bladder adenocarcinoma in a female patient with multiple primary malignant tumors and to provide systematic review of the available literature. Materials and Methods: A 67-year-old female patient was admitted with altered general condition and anuria. The past medical history of the patient included malignant melanoma (2014), cervical cancer (2017), colon cancer (2021), obstructive anuria (2023), and liver metastasectomy (2023). Transurethral resection of bladder tumor was performed for bladder tumors. Results: Contrast CT highlighted multiple pulmonary metastases, a poly nodular liver conglomerate, retroperitoneal lymph node, II/III grade left ureterohydronephrosis, and no digestive tract tumor masses. The pathological result of the bladder resection showed an infiltrative adenocarcinoma. Conclusions: The difference between primary bladder adenocarcinoma tumor and metastatic colorectal adenocarcinoma is the key for the future therapeutic strategy. Identification and assessment of risk factors such as viral infection, radiotherapy, chemotherapy, smoking, and genetics are pivotal in understanding and managing multiple primary malignant tumors. Personalized prevention strategies and screening programs may facilitate the early detection of these tumors, whether synchronous or metachronous. The use of multicancer early detection (MCED) blood tests for early diagnosis appears promising. However, additional research is needed to standardize these techniques for cancer detection. Full article
(This article belongs to the Special Issue Advances in the Diagnosis and Management of Urologic Diseases)
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