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Diagnostics
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Advances in Diagnostic and Therapeutic Endoscopic Ultrasonography for Gastrointestinal Diseases
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Advances in Diagnostic and Therapeutic Endoscopic Ultrasonography for Gastrointestinal Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (31 January 2023) | Viewed by 8504

Special Issue Editors

Dr. Hsuheng Yen

E-Mail Website
Guest Editor
Division of Gastroenterology, Department of Internal Medicine, Changhua Christian Hospital, Changhua 500, Taiwan
Interests: enteroscopy; inflammatory bowel disease; endoscopic submucosal resection
Special Issues, Collections and Topics in MDPI journals
Dr. Yen Chih Lin

E-Mail Website
Guest Editor
Division of Gastroenterology, Department of Internal Medicine, Changhua Christian hospital, Changhua, Taiwan
Interests: gastroendoscopy; gastroenterology

Special Issue Information

Dear Colleagues, 

Endoscopic ultrasound (EUS) is a minimally invasive procedure that is performed to assess gastrointestinal tract diseases. The use of EUS allows clinicians to obtain detailed images of the lining and walls of the digestive tract and the nearby organs such as the pancreas, liver, and lymph nodes. When combined with a therapeutic procedure, EUS allows clinicians to sample tissue for diagnosis. EUS with fine-needle aspiration or biopsy has emerged as a minimally invasive alternative to exploratory surgery.

The present Special Issue aims to highlight recent advances in EUS for the management of gastrointestinal tract disorders, focusing on, but not limited to, its role in disease diagnosis, as well as novel therapeutic EUS approaches. Studies on the use of artificial intelligence in the field of endoscopy and EUS are also welcome.

Dr. Hsuheng Yen
Dr. Yen Chih Lin
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (4 papers)

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11 pages, 635 KiB  
Article
Comparison of Adverse Events of Different Endoscopic Ultrasound-Guided Tissue Acquisition Methods: A Single-Center Retrospective Analysis
by Yen-Chih Lin, Hsu-Heng Yen, Siou-Ping Huang, Kai-Lun Shih and Yang-Yuan Chen
Diagnostics 2022, 12(9), 2123; https://doi.org/10.3390/diagnostics12092123 - 1 Sep 2022
Cited by 2 | Viewed by 1924
Abstract
The efficacy of new generation endoscopic ultrasound-guided biopsy needles has been promising in recent years. Yet, comparing these needles’ diagnostic yield and safety to conventional needles is not well-known. Our study aims to compare the adverse events of endoscopic ultrasound-guided tissue acquisition (EUS-TA) [...] Read more.
The efficacy of new generation endoscopic ultrasound-guided biopsy needles has been promising in recent years. Yet, comparing these needles’ diagnostic yield and safety to conventional needles is not well-known. Our study aims to compare the adverse events of endoscopic ultrasound-guided tissue acquisition (EUS-TA) with different types of needles, including FNA needles, FNB needles with a Franseen tip and FNB needles with a reverse bevel. Furthermore, we will analyze the risk factors, including tumor vascularity, different needle types, and the underlying disease, which may impact the safety of the procedures. From May 2014 to December 2021, 192 consecutive EUS-TAs were performed on pancreatic and peripancreatic lesions in our hospital using different types of FNA and FNB needles. We retrospectively reviewed the data and identified the risk factors for EUS-TA-related complications. As a result, the hypervascular tumor is a significant risk factor for adverse events in our multivariate analysis, with an odds ratio of 4.96 (95% CI 1.33–18.47), while liver cirrhosis is one of the risk factors for adverse events during EUS-TA, with an odds ratio of 5.3 (95% CI 1.1–25.6). However, the risk of adverse events did not increase using Franseen-tip needles, compared to conventional FNA or FNB needles with a reverse bevel. In conclusion, we must be more cautious in patients with liver cirrhosis and hypervascular tumors, such as pancreatic neuroendocrine tumors, when performing EUS-guided tissue acquisition. Full article
(This article belongs to the Special Issue Advances in Diagnostic and Therapeutic Endoscopic Ultrasonography for Gastrointestinal Diseases)
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11 pages, 1922 KiB  
Article
Quantitative Software Analysis of Endoscopic Ultrasound Images of Pancreatic Cystic Lesions
by Bánk Keczer, Márton Benke, Tamás Marjai, Miklós Horváth, Pál Miheller, Ákos Szücs, László Harsányi, Attila Szijártó and István Hritz
Diagnostics 2022, 12(9), 2105; https://doi.org/10.3390/diagnostics12092105 - 30 Aug 2022
Viewed by 1441
Abstract
Endoscopic ultrasonography (EUS) is the most accurate imaging modality for the evaluation of different types of pancreatic cystic lesions. Our aim was to analyze EUS images of pancreatic cystic lesions using an image processing software. We specified the echogenicity of the lesions by [...] Read more.
Endoscopic ultrasonography (EUS) is the most accurate imaging modality for the evaluation of different types of pancreatic cystic lesions. Our aim was to analyze EUS images of pancreatic cystic lesions using an image processing software. We specified the echogenicity of the lesions by measuring the gray value of pixels inside the selected areas. The images were divided into groups (serous cystic neoplasm /SCN/, intraductal papillary mucinous neoplasms and mucinous cystic neoplasms /Non-SCN/ and Pseudocyst) according to the pathology results of the lesions. Overall, 170 images were processed by the software: 81 in Non-SCN, 30 in SCN and 59 in Pseudocyst group. The mean gray value of the entire lesion in the Non-SCN group was significantly higher than in the SCN group (27.8 vs. 18.8; p < 0.0005). The area ratio in the SCN, Non-SCN and Pseudocyst groups was 57%, 39% and 61%, respectively; significantly lower in the Non-SCN group than in the SCN or Pseudocyst groups (p < 0.0005 and p < 0.0005, respectively). The lesion density was also significantly higher in the Non-SCN group compared to the SCN or Pseudocyst groups (4186.6/mm2 vs. 2833.8/mm2 vs. 2981.6/mm2; p < 0.0005 and p < 0.0005, respectively). The EUS image analysis process may have the potential to be a diagnostic tool for the evaluation and differentiation of pancreatic cystic lesions. Full article
(This article belongs to the Special Issue Advances in Diagnostic and Therapeutic Endoscopic Ultrasonography for Gastrointestinal Diseases)
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9 pages, 1879 KiB  
Article
Predicting Factors for Pancreatic Malignancy with Computed Tomography and Endoscopic Ultrasonography in Chronic Pancreatitis
by Jian-Han Lai, Keng-Han Lee, Chen-Wang Chang, Ming-Jen Chen and Ching-Chung Lin
Diagnostics 2022, 12(4), 1004; https://doi.org/10.3390/diagnostics12041004 - 15 Apr 2022
Cited by 4 | Viewed by 1986
Abstract
Diagnosing pancreatic malignancy is challenging, especially in patients with chronic pancreatitis (CP). Endoscopic ultrasonography (EUS) is a promising diagnostic procedure for discriminating between malignancy and CP. We aimed to investigate the predictive factors and reliability of computed tomography (CT) and EUS for differentiating [...] Read more.
Diagnosing pancreatic malignancy is challenging, especially in patients with chronic pancreatitis (CP). Endoscopic ultrasonography (EUS) is a promising diagnostic procedure for discriminating between malignancy and CP. We aimed to investigate the predictive factors and reliability of computed tomography (CT) and EUS for differentiating pancreatic mass lesions and the diagnostic accuracy of EUS-FNA or FNB in patients with CP. Forty patients with CP, receiving CT and EUS-FNA or FNB for pancreatic mass lesion evaluation, were enrolled in the study. Patients’ data, CT and EUS characteristics, image-based diagnosis, cytopathology, and final diagnosis were recorded. EUS was superior to CT in terms of diagnostic accuracy (92.5% vs. 82.5%, p = 0.02). Both CT and EUS showed significant predictive factors (all p < 0.05) with the tumor image hypoattenuation pattern or vessel invasion on CT and pancreatic duct dilatation, or distal pancreatic atrophy on EUS. EUS imaging is a reliable modality for evaluating pancreatic lesions, even with a CP background. The EUS image has a higher diagnostic accuracy than CT. Predicting factors, including hypoechoic pattern, pancreatic duct dilatation, and distal pancreas atrophy, may help to differentiate benign or malignant in patients with CP. Full article
(This article belongs to the Special Issue Advances in Diagnostic and Therapeutic Endoscopic Ultrasonography for Gastrointestinal Diseases)
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7 pages, 1238 KiB  
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Groove Pancreatitis—Tumor-like Lesion of the Pancreas
by Gabriella Gábos, Carmen Nicolau, Alexandra Martin and Ofelia Moșteanu
Diagnostics 2023, 13(5), 866; https://doi.org/10.3390/diagnostics13050866 - 24 Feb 2023
Cited by 3 | Viewed by 2351
Abstract
Groove pancreatitis (GP) is an uncommon appearance of pancreatitis represented by fibrous inflammation and a pseudo-tumor in the area over the head of the pancreas. The underlying etiology is unidentified but is firmly associated with alcohol abuse. We report the case of a [...] Read more.
Groove pancreatitis (GP) is an uncommon appearance of pancreatitis represented by fibrous inflammation and a pseudo-tumor in the area over the head of the pancreas. The underlying etiology is unidentified but is firmly associated with alcohol abuse. We report the case of a 45-year-old male patient with chronic alcohol abuse who was admitted to our hospital with upper abdominal pain radiating to the back and weight loss. Laboratory data were within normal limits, except for the level of carbohydrate antigen (CA) 19-9. An abdominal ultrasound and computed tomography (CT) scan revealed swelling of the pancreatic head and duodenal wall thickening with luminal narrowing. We performed an endoscopic ultrasound (EUS) with fine needle aspiration (FNA) from the markedly thickened duodenal wall and the groove area, which revealed only inflammatory changes. The patient improved and was discharged. The principal objective in managing GP is to exclude a diagnosis of malignancy, whilst a conservative approach might be more acceptable for patients instead of extensive surgery. Full article
(This article belongs to the Special Issue Advances in Diagnostic and Therapeutic Endoscopic Ultrasonography for Gastrointestinal Diseases)
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