The Immunological Basis of Genesis of Gastrointestinal Cancer and Its Diagnostic and Therapeutic Implications
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".
Deadline for manuscript submissions: closed (30 November 2020) | Viewed by 5990
Special Issue Editors
2. Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
3. Health, Biological & Experimental Sciences, University of Coventry, Coventry CV1 5FB, UK
4. School of Health Sciences, University of Leicester, Leicester LE1 7RH, UK
Interests: colon cancer biomarker; volatile organic compounds; bile acid pathophysiology and artificial intelligence
Special Issues, Collections and Topics in MDPI journals
Interests: general surgery; hepatobiliary & pancreatic surgery; kidney and liver transplant
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
An immunopathological understanding behind the genesis of various gastrointestinal cancers, including liver, colorectal, and pancreatic cancer, is needed. The introduction of immunomodulatory changes behind immune evasion has a substantial effect on the progression of cancer, and has brought significant changes in the diagnostic categorization and therapeutic approaches. The molecular characterization of the immune evasion mechanism has led to the identification of favorable and unfavorable immunological attributes linked to clinical outcomes.
The rapid advancement and expansion in the knowledge of immunomodulatory changes and the reinstatement of immunity has evolved in the diagnosis and management of these cancers; hence, this Special Issue of Diagnostics intends to add to the current knowledge with key articles that critically outline the diagnosis and therapeutic challenges related to gastrointestinal cancers, notably liver, pancreatic, and colorectal. Furthermore, it will also accept articles addressing impact of Covid-19 on patients receiving immunotherapy or those who have had organ transplants.
Prof. Dr. Ramesh P. Arasaradnam
Dr. Kumar Jayant
Guest Editors
Manuscript Submission Information
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Keywords
- Hepatocellular carcinoma
- Cholangiocarcinoma
- Pancreatic carcinoma
- Neuroendocrine tumour of pancreas
- Colorectal carcinoma
- Colorectal liver metastasis
- Immunomodulation
- Checkpoint inhibitors
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