Coronavirus and Brain: Diagnosing and Treating COVID-19’s Neurological Effects

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: closed (18 November 2022) | Viewed by 9214

Special Issue Editors


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Guest Editor
1. Brain Research, Innovation and Translation Lab (BRITL), Hawaii Pacific Neuroscience, Honolulu, HI, USA
2. Department of Medicine (Neurology) John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI 96813, USA
3. Graduate Faculty, Clinical & Translational Research, Department of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI 96813, USA
Interests: neurology; neuroscience; neuroimmunology; COVID-19
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. Brain Research, Innovation and Translation Lab (BRITL), Hawaii Pacific Neuroscience, Honolulu, HI, USA
2. Department of Medicine (Neurology) John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI 96813, USA
3. Graduate Faculty, Clinical & Translational Research, Department of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI 96813, USA
Interests: neurology; neuroscience; neuroimmunology; COVID-19
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Neurological complications of Coronavirus disease 2019 (COVID-19) were first recognized during the initial outbreak in Wuhan, China. Since then, a great deal of information has been shared about the neurological aspects of COVID-19, including acute neurological manifestations, such as encephalopathy, cerebrovascular diseases, neuromuscular diseases, and smell and taste disorders. Long-term persistent complications, such as the cognitive effects of COVID-19, are equally important. Other issues include management of immunosuppressive therapy and neurological side effects associated with COVID-19 treatments and vaccines. A better understanding of the neuropathogenesis, including neuronal and immune dysfunction, renin–angiotensin system dysfunction and viral invasion of the nervous system, will enhance our understanding of these clinicopathologic conditions.  

We dedicate this Special Issue of “Coronavirus and Brain: Diagnosing and Treating COVID-19’s Neurological Effects” as a “Call for Action”, and invite the medical and scientific community to join us in raising awareness promoting early and accurate diagnosis. This will result in more favorable treatments and outcomes for the growing number of patients worldwide who are affected by COVID-19.

Prof. Dr. Jason Viereck
Prof. Dr. Kore Kai Liow
Guest Editors

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Published Papers (1 paper)

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7 pages, 1952 KiB  
Case Report
Sudden Sensorineural Hearing Loss after Third Dose Booster of COVID-19 Vaccine Administration
by Federica Zoccali, Francesca Cambria, Andrea Colizza, Massimo Ralli, Antonio Greco, Marco de Vincentiis, Carla Petrella, Marco Fiore, Antonio Minni and Christian Barbato
Diagnostics 2022, 12(9), 2039; https://doi.org/10.3390/diagnostics12092039 - 23 Aug 2022
Cited by 10 | Viewed by 8827
Abstract
Coronavirus disease 2019 (COVID-19) was declared a pandemic due to its rapid spread worldwide, and its vaccination campaign is considered one of the most historic public hygiene measures in modern medicine. Sudden sensorineural hearing loss (SSHL) is a common emergency that affects patient’s [...] Read more.
Coronavirus disease 2019 (COVID-19) was declared a pandemic due to its rapid spread worldwide, and its vaccination campaign is considered one of the most historic public hygiene measures in modern medicine. Sudden sensorineural hearing loss (SSHL) is a common emergency that affects patient’s quality of life and requires rapid treatment with steroids. The etiology could be viral or vascular even though in most cases it remains unknown (idiopathic SSHL). During the SARS-CoV-2 vaccination campaign, several rare but serious adverse events have been reported including thrombosis with thrombocytopenia syndrome, myocarditis, and Guillain-Barré Syndrome. ENT adverse events after vaccination were reported too, including cases of sudden sensorineural hearing loss (SSHL), vestibular neuronitis and audio vestibular disorders (such as tinnitus, dizziness, and vertigo). For the first time here, we reported two cases of SSHL after third administration of COVID-19 mRNA vaccine. Even if there is not clear evidence of an association between SSHL and vaccination, adverse effects should be kept in mind since viral infection could be the etiology of SSHL. Full article
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