New Advances in Drugs/Vaccines against Infectious Diseases

A special issue of Infectious Disease Reports (ISSN 2036-7449). This special issue belongs to the section "Immunology and Vaccines".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 1911

Special Issue Editors


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Guest Editor
Department of Molecular and Translational Medicine, Center of Emphasis in Infectious Diseases, Texas Tech University Health Sciences Center El Paso, El Paso, TX 79905, USA
Interests: infectious disease; antimicrobial resistance; drugs/vaccines against infectious pathogens
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Guest Editor
School of Pharmacy, Lake Erie College of Osteopathic Medicine (LECOM), Erie, PA 16509, USA
Interests: pulmonary infectious diseases; lung regeneration and repair; immunopharmacology; neuropharmacology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Infectious diseases are a serious and growing public health problem worldwide, causing high mortality and morbidity. They are caused by different classes of pathogenic microorganisms, such as bacteria, viruses, fungi, or parasites. Based on the nature of a pathogen, it can spread from person to person, from animal to human, or through other means, such as air, water, food, or soil. We already have complicated diseases like AIDS, tuberculosis, malaria, etc. to deal with, which affect a greater population of people worldwide. The recent COVID-19 pandemic taught us a lesson by taking more than 6.9 million human lives, where the USA alone has seen more than 1 million deaths. Even though we have ultra-modern technologies, there are many complications in finding solutions to these infectious diseases. To overcome these obstacles, we are in need of efficient and timely treatments with potential drugs or vaccines. Pathogens cause diseases that range from being mild to life-threatening, and this topic focuses specifically on infections that spread in hospitals and other healthcare settings, infections that are resistant to antibiotics, emerging or re-emerging infectious diseases, infectious diseases with a lack of vaccines, multidrug-resistant pathogens, tuberculosis, and COVID-19.

We foresee that our research topic will bring all novel research against infectious diseases together in one place. We welcome potential topics for submission to this Special Issue, including (but not limited to) the following:

  1. Antimicrobial drugs: natural, synthetic, repurposed, nanoparticle-based, etc.
  2. Vaccines: recombinant, DNA vaccine, prime boost, mRNA, live attenuated vaccine, etc.
  3. System biology approach in drug/vaccine development.
  4. Discovery of drugs/vaccine molecular mechanisms using omics technologies—genomics, proteomics, and metabolomics.
  5. New approaches in drug/vaccine development against COVID-19 and tuberculosis.
  6. Study of host microbiome after microbial infection or drug/vaccine treatment.

Dr. Raja Veerapandian
Dr. Jagdish Joshi
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Infectious Disease Reports is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • infectious diseases
  • drugs
  • vaccines
  • in silico
  • system biology
  • multi-omics
  • microbiome
  • COVID-19
  • tuberculosis

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Published Papers (1 paper)

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Research

10 pages, 569 KiB  
Article
Pertussis Notification Rate and Tdpa Vaccine/Booster Coverage in Adults: An Opportunity for an Epidemiological Observatory in Primary Care
by Francesco Lapi, Ettore Marconi, Iacopo Cricelli, Alessandro Rossi, Tecla Mastronuzzi, Giovanni Gabutti and Claudio Cricelli
Infect. Dis. Rep. 2024, 16(5), 870-879; https://doi.org/10.3390/idr16050068 - 2 Sep 2024
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Abstract
Background: In recent years, Europe has experienced a significant increase in pertussis cases. One reason behind this rise is the decline in diphtheria–tetanus–pertussis (dTap) booster coverage among adults. Currently, Italy lacks a reliable monitoring system to track pertussis infections and vaccine coverage [...] Read more.
Background: In recent years, Europe has experienced a significant increase in pertussis cases. One reason behind this rise is the decline in diphtheria–tetanus–pertussis (dTap) booster coverage among adults. Currently, Italy lacks a reliable monitoring system to track pertussis infections and vaccine coverage among adults. We therefore evaluated the reliability of a primary care framework to respond to this need. Methods: Using an Italian primary care database for individuals aged 15 or above, we determined the pertussis infection notification rate and dTap vaccine/booster coverage for the timeframe of 2009–2022. Results: In the overall population, we obtained a lifetime occurrence rate of pertussis infections of 7.52 per 10,000 individuals. The annual incidence rates of pertussis infections ranged from 0.008 to 0.001 per 10,000 person-years between 2009 and 2022. A rising trend in dTap vaccine coverage rate (ranging from 8.72 to 16.54 vaccines per 10,000 individuals) was observed during the same period. Notably, those aged 65 or older, smokers, and/or individuals with immunodeficiencies were more likely to receive the dTap vaccine compared to the general population. Conclusions: Given the organization of the Italian public health system, this primary care network might act as a reliable epidemiological monitoring system to keep track of pertussis infections and dTap vaccine coverage in adults. Pertussis cases were underreported, and there was a low uptake of vaccines and boosters. Therefore, it is crucial to closely monitor pertussis notifications and dTap administrations and develop intervention strategies at the national level to enhance vaccine-related prevention. Full article
(This article belongs to the Special Issue New Advances in Drugs/Vaccines against Infectious Diseases)
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