Stem Cell Therapy for Autism and Other Neuropsychiatric Disorders
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Mental Health".
Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 8801
Special Issue Editors
Interests: autism; gene expression; cell biology; stem cells; apoptosis; neuroinflammation
Special Issues, Collections and Topics in MDPI journals
Interests: cellular senescence; radiation therapy; stem cells; cell cycle
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Autism spectrum disorders (ASDs) are heterogenous neurodevelopmental pathologies characterized by social interaction and communication impairments, as well as by restricted, repetitive, and stereotyped patterns of behaviour. ASDs are multifactorial disorders, with epigenetic mechanisms underlying their development. Immune dysfunctions have been confirmed observations for children with ASDs. Together with other related neuropsychiatric insults, ASDs have been recognized as a public health problem. Currently, there are no definitive treatments for ASDs’ core symptoms. Pharmacological intervention does not affect all of the core symptoms, providing only partial relief for some of the dysfunctional behaviours. The current available strategies for ASDs can be grouped into behavioural, nutritional, and drug therapy.
Cell therapy represents great promise for the future of molecular and regenerative medicine. Several types of cells offer a valid approach to curing several untreatable human neurodegenerative diseases. Recent advances in the molecular mechanisms of psychiatric conditions indicate that cell therapy could be a potent treatment for these syndromes.
We invite authors to contribute original research articles and review articles that will focus on the novel findings on the molecular, biochemical, and cellular basis of neuropsychiatric disorders, with special emphasis on ASDs, in order to provide scientific rationale for cell application.
Potential topics include, but are not limited to, the following:
Recent insights into neuropsychiatric disorders research;
Identification of potential ASD biomarkers;
Recent advances in animal models;
Potential therapeutical application of cells;
Secretome biology and application.
Dr. Dario Siniscalco
Dr. Nicola Alessio
Guest Editors
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Keywords
- Autism spectrum disorders
- Psychiatric disorders
- Stem cells
- Cellular therapy
- Guidelines
- Neuroimmunology
- Epigenetic and gene expression
- microRNA and microvesicles
- Neural plasticity
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