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A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Health Behavior, Chronic Disease and Health Promotion".

Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 5723

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Special Issue Editors

Dr. Iwona Gorczyca-Głowacka

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Guest Editor

Collegium Medicum, Jan Kochanowski University, 25-317 Kielce, Poland
Interests: atrial fibrillation; anticoagulant therapy; stroke prevention

Dr. Beata Uziębło-Życzkowska

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Guest Editor

Department of Cardiology and Internal Diseases, Military Institute of Medicine, 04-141 Warsaw, Poland
Interests: cardiovascular imaging; echocardiography; atrial fibrillation

Special Issue Information

Dear Colleagues,

Cardiovascular diseases (CVDs) are a global epidemic and are among the most impressive demographic phenomena around the world. CVDs are the leading cause of death globally, taking an estimated 17.9 million lives each year. CVDs are a group of disorders of the heart and blood vessels and include coronary heart disease, cerebrovascular disease, peripheral disease, rheumatic heart disease, and other conditions. More than four out of five CVD deaths are due to heart attacks and strokes, and one-third of these deaths occur prematurely in people under 70 years of age.

Basic research and development of new therapeutic approaches used for prevention and treatment of CVDs have begun unveiling the molecular and clinical complexity of CVDs. However, it is still necessary to investigate the risk factors of CVDs in order to ameliorate patient care.

The aim of this Special Issue is to provide a collection of original research articles, comprehensive reviews, and communications, highlighting the latest frontiers in basic, translational, and clinical research. Acceptable topics include the use of new technologies in diagnosis and treatment of CVDs. Particular interest will be given to genetic, molecular, clinical, and immune biomarkers, as well as to novel invasive tools.

Dr. Iwona Gorczyca-Głowacka
Dr. Beata Uziębło-Życzkowska
Guest Editors

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Keywords

atherosclerosis
cardiovascular disease
coronary artery diseases
peripheral artery disease
risk factors
thromboembolic disease

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Research

9 pages, 1298 KiB

Open AccessArticle

The Importance of a Distance between the Lines Encircling Pulmonary Veins in Atrial Fibrillation Ablation on First-Pass Isolation Ratio and Clinical Outcomes

by Krystian Krzyżanowski, Marek Kiliszek, Beata Uziębło-Życzkowska, Magdalena Smalc-Stasiak, Aleksandra Winkler and Paweł Krzesiński

Int. J. Environ. Res. Public Health 2023, 20(7), 5250; https://doi.org/10.3390/ijerph20075250 - 24 Mar 2023

Cited by 1 | Viewed by 1899

Abstract

Introduction: How wide the encircling line is made may influence the outcomes of pulmonary vein isolation (PVI). In the present study we hypothesised that the distance between the lines encircling the pulmonary veins may correspond with the extent of wide antral circumferential ablation (WACA). The aim of the study was to assess the impact of the distance and the area between the lines on the posterior wall of the left atrium on first-pass isolation rate and 12-month freedom from atrial arrhythmia in patients undergoing PVI ablation. Methods and results: One hundred sixteen patients underwent circumferential ablation index (AI)-guided PVI. The distance between the encircling ablation lines was measured off-line between the uppermost points (right and left) and the lowest points and as the area between the encircling lines on the posterior wall. The first-pass isolation rate and 12-month freedom from atrial arrhythmia were 59% and 73%, respectively. Distance between the encircling lines measured linearly or as the area of the posterior wall, assessed as direct values or indexed to left atrial dimensions, did not differ between patients with and without first-pass isolation or between patients with and without recurrences of atrial arrhythmia. Conclusions: The distance between the ablation lines did not influence the rate of first-pass isolation and arrhythmia recurrence in the long-term follow-up after PVI procedures incorporating the ablation index protocol. Full article

(This article belongs to the Special Issue Advancements in Cardiovascular Disease Research and Treatment Strategies)

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12 pages, 1356 KiB

Open AccessArticle

Coronary Artery Disease and Inflammatory Activation Interfere with Peripheral Tissue Electrical Impedance Spectroscopy Characteristics—Initial Report

by Tomasz Urbanowicz, Michał Michalak, Ewa Marzec, Anna Komosa, Krzysztof J. Filipiak, Anna Olasińska-Wiśniewska, Anna Witkowska, Michał Rodzki, Andrzej Tykarski and Marek Jemielity

Int. J. Environ. Res. Public Health 2023, 20(3), 2745; https://doi.org/10.3390/ijerph20032745 - 3 Feb 2023

Cited by 3 | Viewed by 1809

Abstract

Background: The electrical properties of cells and tissues in relation to energy exposure have been investigated, presenting their resistance and capacitance characteristics. The dielectric response to radiofrequency fields exhibits polarization heterogeneity under pathological conditions. The aim of the study was to analyze the differences in changes in resistance and capacitance measurements in the range from 1 kHz to 1 MHz, combined with an assessment of the correlation between the results of electrical impedance spectroscopy (EIS) and inflammatory activation. Methods: In the prospective study, EIS was performed on the non-dominant arm in 29 male patients (median (Q1–Q3) age of 69 (65–72)) with complex coronary artery disease and 10 male patients (median (Q1–Q3) age of 66 (62–69)) of the control group. Blood samples were collected for inflammatory index analysis. Results: The logistic regression analysis revealed a negative correlation with inflammatory indexes, including neutrophil to lymphocyte ratio (NLR) in the CAD group in the frequency of 30 kHz (p = 0.038, r = −0.317) regarding EIS resistance measurements and a positive correlation in CAD group in the frequency of 10 kHz (p = 0.029, r = −0.354) regarding EIS capacitance. Conclusions: The bioelectric characteristics of peripheral tissues measured by resistance and capacitance in EIS differ in patients with coronary artery disease and in the control group. Electrical impedance spectroscopy reveals a statistically significant correlation with inflammatory markers in patients with CAD. Full article

(This article belongs to the Special Issue Advancements in Cardiovascular Disease Research and Treatment Strategies)

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13 pages, 1518 KiB

Open AccessArticle

Impact of Air Pollution and COVID-19 Infection on Periprocedural Death in Patients with Acute Coronary Syndrome

by Janusz Sielski, Małgorzata Anna Jóźwiak, Karol Kaziród-Wolski, Zbigniew Siudak and Marek Jóźwiak

Int. J. Environ. Res. Public Health 2022, 19(24), 16654; https://doi.org/10.3390/ijerph192416654 - 11 Dec 2022

Cited by 2 | Viewed by 1501

Abstract

Air pollution and COVID-19 infection affect the pathogenesis of cardiovascular disease. The impact of these factors on the course of ACS treatment is not well defined. The purpose of this study was to evaluate the effects of air pollution, COVID-19 infection, and selected clinical factors on the occurrence of perioperative death in patients with acute coronary syndrome (ACS) by developing a neural network model. This retrospective study included 53,076 patients with ACS from the ORPKI registry (National Registry of Invasive Cardiology Procedures) including 2395 COVID-19 (+) patients and 34,547 COVID-19 (−) patients. The neural network model developed included 57 variables, had high performance in predicting perioperative patient death, and had an error risk of 0.03%. Based on the analysis of the effect of permutation on the variable, the variables with the greatest impact on the prediction of perioperative death were identified to be vascular access, critical stenosis of the left main coronary artery (LMCA) or left anterior descending coronary artery (LAD). Air pollutants and COVID-19 had weaker effects on end-point prediction. The neural network model developed has high performance in predicting the occurrence of perioperative death. Although COVID-19 and air pollutants affect the prediction of perioperative death, the key predictors remain vascular access and critical LMCA or LAD stenosis. Full article

(This article belongs to the Special Issue Advancements in Cardiovascular Disease Research and Treatment Strategies)

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