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Applications of Natural Products in Sustainable Biotechnology

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: closed (28 March 2024) | Viewed by 2658

Special Issue Editors


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Guest Editor
Institute of Translational Pharmacology (IFT), National Research Council (CNR), Via Ugo La Malfa 153, 90146 Palermo, Italy
Interests: echinoderms; marine invertebrates; ecological immunology- innate immunity; bioactive molecules; metabolism; signalling
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Guest Editor
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d’Alcontres, 31, 98166 Messina, Italy
Interests: alternative nutritional sources, bioactive molecules, aquaculture; environmental toxicology; oxidative stress; immune response, cell and molecular biology
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Institute of Translational Pharmacology (IFT), National Research Council (CNR), Via Ugo La Malfa 153, 90146 Palermo, Italy
Interests: host-pathogen interaction; virulence factors; inflammation; bacterial pathogens; immunogens; protein-protein interaction

Special Issue Information

Dear Colleagues,

Bacteria and invertebrates, the most numerous forms of life in the world, synthesize bioactive molecules to protect themselves from dynamic and challenging environments and to acquire an advantage in survival competition. These organisms represent an important source of naturally exploitable compounds having high structural diversity and unique pharmacological or biological activities (e.g., antimicrobial, quorum sensing, antiviral, anticancer, antioxidant, and pro- or anti-inflammatory activities) due to natural selection and evolutionary processes.

In this special issue, we are collecting reviews and articles about the role of natural products in discovering, and developing natural and inexpensive solutions for sustainable biotechnology applications in medicine, nutraceutical, agriculture, and environmental protection.

Dr. Annalisa Pinsino
Dr. Alessia Giannetto
Dr. Salvatore Papasergi
Guest Editors

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Keywords

  • macromolecules
  • metabolisms
  • biological functions
  • biosynthetic pathways
  • waste valorisation
  • cellular mechanisms

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Published Papers (1 paper)

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Research

11 pages, 2187 KiB  
Article
Innovative Approaches for Food: Using Natural Phenolic-Rich Extracts to Produce Value-Added Fresh Pasta
by Sandra M. Gomes, Daniela Albuquerque and Lúcia Santos
Int. J. Mol. Sci. 2023, 24(15), 12451; https://doi.org/10.3390/ijms241512451 - 5 Aug 2023
Cited by 4 | Viewed by 1897
Abstract
Cereal-based products, which are rich in carbohydrates, are widely consumed worldwide; however, this type of food lacks other nutrients. Phenolic compounds from natural sources, such as Moringa oleifera, can be incorporated into these products to increase their nutritional and biological value. In [...] Read more.
Cereal-based products, which are rich in carbohydrates, are widely consumed worldwide; however, this type of food lacks other nutrients. Phenolic compounds from natural sources, such as Moringa oleifera, can be incorporated into these products to increase their nutritional and biological value. In this study, a phenolic-rich extract was obtained from M. oleifera leaf powder using a Soxhlet extractor. The extract obtained presented a total phenolic content of 79.0 mg of gallic acid equivalents/g and the ABTS and DPPH assays showed that the extract can act as an anti-oxidant agent, with IC50 values of 205.2 mg/L and 636.0 mg/L, respectively. Afterwards, fresh pasta was produced and the extract was incorporated into the pasta to improve its biological properties and extend its shelf-life. The results demonstrated that the addition of M. oleifera to the fresh pasta increased its anti-oxidant capacity and did not interfere with the cooking properties of the product. Moreover, the fortified pasta presented an increased shelf-life, since the extract conferred protection against microbial contamination for longer periods of time. Therefore, these findings showed that the incorporation of phenolic-rich extracts from natural sources (such as M. oleifera) is a feasible sustainable biotechnological approach to produce value-added cereal-based products. Full article
(This article belongs to the Special Issue Applications of Natural Products in Sustainable Biotechnology)
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