Advances in the Treatment of Acute and Chronic Pain
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 December 2024 | Viewed by 116
Special Issue Editors
Interests: drug design; organic chemistry; molecular modelling; enzymology; metalloenzymes; carbonic anhydrases; GPCR; enzyme modulators; anticancer; antiinfectives; anti-inflammatory; anti-Alzheimer; multi-target directed ligands; spectroscopic studies; structure-based design; molecular dynamics
Special Issues, Collections and Topics in MDPI journals
Interests: pain pharmacology; chronic pain; inflammatory pain; chemotherapy induced neuropathic pain; trauma-induced neuropathic pain, glial cells; hyperalgesia; allodynia; in vivo approach; in vitro approach; therapeutic agents; pharmacological mechanism
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The management of acute and chronic pain still represents a challenge in clinical practice, requiring continued advances in therapeutic approaches. Pharmacological interventions, ranging from traditional analgesics to novel targeted therapies, are increasingly complemented by advancements in medicinal chemistry that optimize drug efficacy, selectivity, and safety profiles.
This Special Issue aims to explore recent developments at the intersection of pharmacology and medicinal chemistry in the treatment of pain, providing a comprehensive overview of recent advancements in pain management. By bridging disciplines, this Special Issue seeks to accelerate the translation of scientific discoveries into clinical practice, ultimately improving the quality of life for patients suffering from acute and chronic pain conditions.
Key topics include the design and synthesis of novel analgesic agents, mechanisms of action underlying emerging therapies, and the pharmacokinetic and pharmacodynamic properties critical for clinical application. Contributions will highlight innovative drug delivery systems, such as nanotechnology and prodrug strategies, aimed at enhancing therapeutic outcomes and patient compliance for a more personalized pain management.
Furthermore, this Special Issue will address the challenges of opioid-sparing strategies and the development of non-opioid alternatives. Insights into the molecular mechanisms of pain signaling and the role of neuroinflammation will inform the design of next-generation analgesics.
Dr. Alessio Nocentini
Dr. Laura Micheli
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- pain management
- acute pain
- chronic pain
- opioids
- non-opioid analgesics
- drug design
- nociception
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
