Editorial Board Members’ Collection Series: "Exploring Molecular Mechanisms in Cancer Biology"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 January 2025 | Viewed by 3319
Special Issue Editors
Interests: cancer cell biology; DNA repair; transposable elements; bioactive molecules; gene expression; stress response; microalgae
Special Issues, Collections and Topics in MDPI journals
Interests: mevalonate pathway; prenylation proteins; cannabinoid and cancer; cell cycle; cancer-related biochemical pathways; cell proliferation; cell signaling; breast cancer; glioblastoma multiforme
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Exploring the molecular mechanisms underlying the formation and progression of cancerous tumors is essential to the development of new strategies for the prevention, diagnosis, and treatment of cancer.
One of the main characteristics of cancer is the uncontrolled proliferation of cells, which can be caused by alterations in the mechanisms that regulate the cell cycle and control cell division and growth. Genetic mutations can disrupt these regulatory mechanisms, allowing cancer cells to divide aberrantly and form tumors. Exploring the molecular mechanisms involved in these genetic mutations can help us to identify the genes responsible for cancer progression and understand how they contribute to tumor formation. In addition to genetic mutations, other molecular mechanisms may also contribute to cancer progression. For example, epigenetic modifications, which do not alter the DNA sequence but affect gene expression, may play an important role in regulating the activity of the genes involved in cell proliferation.
In addition, certain specific proteins may be produced in excess or abnormally in cancer cells, which may favour their proliferation and survival. Identifying these proteins and their mechanisms of action may provide targets for the development of new cancer treatments. The exploration of molecular mechanisms in cancer biology also includes the study of the immune response against cancer cells, the interplay between a tumor and its microenvironment, angiogenesis, increased metabolism, invasion and metastasis processes, the acquisition of resistance, etc.
In short, the exploration of molecular mechanisms in cancer biology plays an essential role in our understanding of the formation and progression of cancerous tumors. It enables new therapeutic targets to be discovered and more effective approaches to cancer prevention and treatment to be developed.
Prof. Dr. Benoît Chénais
Dr. Chiara Laezza
Guest Editors
Manuscript Submission Information
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Keywords
- angiogenesis
- cancer biomarkers
- cancer therapy
- epigenetics
- genetics
- immune response
- metabolism
- metastasis
- mutation
- resistance
- tumor microenvironment
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