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Probiotics in Health and Disease

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".

Deadline for manuscript submissions: 25 June 2025 | Viewed by 109

Special Issue Editor


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Guest Editor
Faculty of Food Technology and Biotechnology, University of Zagreb, 10000 Zagreb, Croatia
Interests: gut microbiota; probiotics; postbiotics; Lactobacillus

Special Issue Information

Dear Colleagues,

Probiotics are intensively used, and, consequently, they have become the regular, first-choice microbial-based therapy for intestinal dysbiosis. This stems from accumulating scientific evidence confirming their functionality in in vitro, in vivo, and (pre)clinical trials. Their importance also results from the knowledge that probiotic species, by balancing intestinal microbiota, in addition to preventing or treating intestinal disorders, can impact diseases linked to the gut–liver–brain axis and many others. Moreover, documented probiotics activities have been recognized in specialized subjects such as newborns and certain patient groups, such as people with irritable bowel diseases. Therefore, this Special Issue invites all studies describing the molecular mechanisms and/or probiotic cellular structures associated with probiotic–host interactions in health or disease. This includes the molecular patterns by which probiotic strains regulate adhesion and colonization processes, exclude enteropathogens, influence the host metabolism, or exert immunomodulation effects, alongside research using omics approaches to study specific dysbioses, with an emphasis on an integrated multiomics overview of the host and the microbiota to understand the underlying mechanisms during conditions of health and disease. This issue is also dedicated to the importance of a critical approach due to increasing probiotic strains becoming available on the market, inviting articles considering the importance of assuring their safety and quality.

Dr. Tena Niseteo is a scientist (Topical Advisory Panel in IJMS), who will assist Professor Novak in managing this Special Issue.

Prof. Dr. Jasna Novak
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • probiotic
  • microbiota
  • quality
  • dysbiosis

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Published Papers

This special issue is now open for submission.
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