Molecular Mechanisms, Biomarkers, and Therapeutic Targets for Endometriosis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 56
Special Issue Editors
Interests: primary endometrial stroma cells; endometriosis; epigenetics, signaling, endocrinology and metabolism
Interests: endometriosis; lncRNAs; imprinting; epigenetics; biomarkers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Endometriosis is a chronic gynecological disease marked by ectopic endometrial-like tissue growth, often causing pain, infertility, and compromised quality of life. The disease pathogenesis involves complex molecular mechanisms, including epigenetic, hormonal, and immunological dysregulation, oxidative stress, chronic inflammation, and fibrogenesis. As the exact mechanisms remain elusive, this Special Issue aims to advance our understanding that eventually could improve the development of novel therapeutic approaches.
While recent advancements emphasize non-invasive diagnostic imaging techniques, particularly magnetic resonance imaging (MRI) and ultrasound, they cannot replace surgery in diagnosing all subtypes of endometriosis. Potential studies that hold promise for non-invasive biomarkers for diagnosing endometriosis and/or progression, such as epigenetic regulators, gene profiles, or specific proteins, will be published in this Special Issue and could eventually complement imaging for a comprehensive, non-invasive diagnostic approach.
Dr. Katharina Proestling
Dr. Iveta Yotova
Guest Editors
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Keywords
- endometriosis
- biomarkers
- inflammation
- fibrosis
- oxidative stress
- epigenetics
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