Microbiota Dysbiosis in Parkinson’s Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 20 March 2025 | Viewed by 430
Special Issue Editor
Special Issue Information
Dear Colleagues,
Parkinson’s disease (PD) is a common neurodegenerative disorder pathophysiologically manifesting with the loss of substantia nigra neurons and the accumulation of α-synuclein throughout the central nervous system. Several genetic and environmental factors are so far known, however since confirmed genetic forms of the disease can be found in around 10% of patients, environmental factors (such as heavy metals, pesticides, sleep disorders, recurrent traumatic brain injury, etc.) and the interaction between genetic factors and the underlying molecular mechanisms likely play a significant role in development of PD. Known factors like recurrent traumatic brain injury, while intestinal and oral microbiota have also increasingly been observed to be imbalanced in PD patients. Whether the microbial dysbiosis in PD precedes the disease or is a consequence of disturbed neuronal communication at the level of the gut-brain axis, remains to be answered. Furthermore, comprehensive characterization of microbial dysbiosis and its cause and effect in PD is especially important since the microbiome is a factor that can be easily influenced by various interventions such as diet and probiotic supplementation, offering novel targets for possible treatment.
This Special Issue aims to provide a platform for molecular mechanistic research on Microbiota Dysbiosis in Parkinson’s Disease with a special focus on potential treatments and novel pathogenic pathways involved in relative disease.
Dr. Anja Kovanda
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Parkinsons’ disease
- microbiome
- intestinal microbiome
- gut microbiome
- oral microbiome
- microbiota
- dysbiosis
- fatty acids
- genetics
- genomics
- sequencing
- 16S RNA
- microbial diversity
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
