The Role of microRNA in Human Diseases 3.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 April 2025 | Viewed by 459
Special Issue Editor
2. Heidelberg Biolabs GmbH, 69120 Heidelberg, Germany
Interests: microRNA (miRNA); siRNA; cancer biology; gene regulation; molecular cloning
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is the continuation of our previous Special Issues, “The Role of microRNA in Human Diseases” and “The Role of microRNA in Human Diseases 2.0”.
MicroRNA (miRNA) is a class of small (about 22 nt long) noncoding RNAs whose main function is in the negative post-transcriptional and translational regulation of gene expression. In most cases, this regulation is mediated by the complementary binding of miRNA to the 3′ UTR of the target mRNA to promote its degradation and/or translational repression. Furthermore, multiple reports have consistently shown that aberrant miRNA expression is associated with various human diseases, including cancer and neurological and cardiovascular diseases. Finally, some host- and virus-encoded miRNAs can contribute to the process of infection by targeting certain mRNAs (both host and viral).
This Special Issue focuses on the roles of aberrant miRNA expression in different human diseases, as well as the characterization of putative miRNA targets for therapeutic intervention. In particular, studies involving advanced deep sequencing methods and novel bioinformatics algorithms for miRNA research (focus on a molecular level) are highly welcomed. The formats for submission include original research reports, reviews, and communications.
Dr. Andrey Turchinovich
Guest Editor
Manuscript Submission Information
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Keywords
- microRNA (miRNA)
- non-coding RNAs
- human diseases
- cancer
- fatty liver
- cardiovascular diseases
- neurological diseases
- viral infection
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