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Advances in Nanotechnology: Nanomaterials and Nanobiocatalyst

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biophysics".

Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 17529

Special Issue Editor

Dr. Sanjay Kumar Singh Patel

E-Mail Website
Guest Editor
Department of Chemical Engineering, Konkuk University, Seoul 05029, Republic of Korea
Interests: Korea nanobiocatalyst; biosensors; anti-microbials; quorum sensing inhibition; microbial pathogen; microbial biotechnology; environmental biotechnology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue on “Advances in Nanotechnology: Nanomaterials and Nanobiocatalysts” will cover a research topic focused on nanotechnology-based applications, especially nanomaterial and biocatalyst preparation and their potential applications, including biocatalyst immobilization on nanomaterials, protein–inorganic hybrids, biosensor, fuel and chemicals, antimicrobials, biotransformation, biodegradation, etc.

In recent decades, a significant development in nanotechnology, especially the synthesis of nanomaterials with improved properties such as controlled size and morphology, high surface area, biocompatibility and rigidity, porous nature and easy modification of their surface to allow for specific binding, has been studied for their broad industrial, medical, and environmental applications. The design and selection of suitable nanomaterials for their potential biotechnological applications is a major challenging area. The recent research advances in nanomaterials-based technology include the uses of nanomaterials for antimicrobials, immobilization supports for biocatalysts, biotransformation (value-added products), energy, biosensors, and bioremediation. On the other hand, the synthesis of protein–inorganic hybrid-based nanobiocatalysts has been found effective for efficient biocatalyst immobilization and their biotechnological applications.

Prof. Dr. Sanjay K. S. Patel
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

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Keywords

  • Nanotechnology
  • Biodegradation
  • Fuel and chemicals
  • Biosensor
  • Biotransformation
  • Immobilization
  • Nanobiocatalyst
  • Protein–inorganic hybrid
  • Antimicrobials

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Published Papers (5 papers)

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Research

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11 pages, 1942 KiB  
Article
Poloxam Thermosensitive Hydrogels Loaded with hFGF2-Linked Camelina Lipid Droplets Accelerate Skin Regeneration in Deep Second-Degree Burns
by Yuan Zhang, Wanying He, Shuhan Zhang, Xingli Hu, Siming Sun, Hongtao Gao, Jie Kong, Hongxiang Liu, Haiyan Li, Xin Liu and Yan Cheng
Int. J. Mol. Sci. 2022, 23(21), 12716; https://doi.org/10.3390/ijms232112716 - 22 Oct 2022
Cited by 6 | Viewed by 1826
Abstract
Burn injuries are difficult to manage due to the defect of large skin tissues, leading to major disability or even death. Human fibroblast growth factor 2 (hFGF2) is known to promote burn wound healing. However, direct administration of hFGF2 to the wound area [...] Read more.
Burn injuries are difficult to manage due to the defect of large skin tissues, leading to major disability or even death. Human fibroblast growth factor 2 (hFGF2) is known to promote burn wound healing. However, direct administration of hFGF2 to the wound area would affect the bioactivity. To provide a supportive environment for hFGF2 and control its release in a steady fashion, in this research, we developed novel thermosensitive poloxam hydrogels delivered with hFGF2-linked Camelina lipid droplets (CLD-hFGF2 hydrogels). Cryopreserved scanning electron microscopy (SEM) results indicated that the incorporation of CLD-hFGF2 does not significantly affect the inner structure of hydrogels. The rheological properties showed that CLD-hFGF2 hydrogels gelated in response to temperature, thus optimizing the delivery method. In vitro, CLD-hFGF2 could be released from hydrogels for 3 days after drug delivery (the release rate was 72%), and the release solution could still promote the proliferation and migration of NIH3T3 cells. In vivo, compared with hydrogels alone or with direct CLD-hFGF2 administration, CLD-hFGF2 hydrogels had the most obvious effect on deep second-degree burn wound healing. This work indicates that CLD-hFGF2 hydrogels have potential application value in burn wound healing. Full article
(This article belongs to the Special Issue Advances in Nanotechnology: Nanomaterials and Nanobiocatalyst)
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7 pages, 3094 KiB  
Article
Dynamic and Static Switching in ITO/SnOx/ITO and Its Synaptic Application
by Jongmin Park, Hyunwoong Park, Daewon Chung and Sungjun Kim
Int. J. Mol. Sci. 2022, 23(17), 9995; https://doi.org/10.3390/ijms23179995 - 2 Sep 2022
Cited by 3 | Viewed by 2055
Abstract
The attempts to devise networks that resemble human minds are steadily progressing through the development and diversification of neural networks (NN), such as artificial NN (ANN), convolution NN (CNN), and recurrent NN (RNN). Meanwhile, memory devices applied on the networks are also being [...] Read more.
The attempts to devise networks that resemble human minds are steadily progressing through the development and diversification of neural networks (NN), such as artificial NN (ANN), convolution NN (CNN), and recurrent NN (RNN). Meanwhile, memory devices applied on the networks are also being studied together, and RRAM is the one of the most promising candidates. The fabricated ITO/SnOX/TaN device showed two forms of current–voltage (I-V) curves, classified as dynamic and static. It was triggered from the forming process, and the difference between the two curves resulted from the data retention measured at room temperature for 103 s. The dynamic curve shows a time-dependent change in the data, and the cause of the data preservation period was considered through X-ray photoelectron spectroscopy (XPS) and linear fitting in conduction mechanisms. To confirm whether the memory performance of the device may be implemented on the synapse, the change in the plasticity was confirmed using a rectangular-shaped pulse. Paired-pulse facilitation (PPF) was implemented, and the change from short-term potentiation (STP) to long-term potentiation (LTP) was achieved. Full article
(This article belongs to the Special Issue Advances in Nanotechnology: Nanomaterials and Nanobiocatalyst)
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14 pages, 4600 KiB  
Article
Investigation of the Antibacterial Properties of Silver-Doped Amorphous Carbon Coatings Produced by Low Pressure Magnetron Assisted Acetylene Discharges
by Valentin Job, Julie Laloy, Vincent Maloteau, Emile Haye, Stéphane Lucas and Sébastien Penninckx
Int. J. Mol. Sci. 2022, 23(1), 563; https://doi.org/10.3390/ijms23010563 - 5 Jan 2022
Cited by 4 | Viewed by 2452
Abstract
Hospital-acquired infections are responsible for a significant part of morbidity and mortality. Among the possible modes of transmission, this study focuses on environmental surfaces by developing innovative antibacterial coatings that can be applied on interior fittings in hospitals. This work aims to optimize [...] Read more.
Hospital-acquired infections are responsible for a significant part of morbidity and mortality. Among the possible modes of transmission, this study focuses on environmental surfaces by developing innovative antibacterial coatings that can be applied on interior fittings in hospitals. This work aims to optimize a coating made of an amorphous carbon matrix doped with silver (a-C:H:Ag) produced by a hybrid PVD/PECVD process and to evaluate its antibacterial activity. We present a coating characterization (chemical composition and morphology) as well as its stability in an ageing process and after multiple exposures to bacteria. The antibacterial activity of the coatings is demonstrated against Escherichia coli (Gram-negative) and Staphylococcus aureus (Gram-positive) bacteria through several bioassays. Moreover, the data suggest a crucial role of silver diffusion towards the surface and nanoparticle formation to explain the very promising anti-bacterial activities reported in this work. Full article
(This article belongs to the Special Issue Advances in Nanotechnology: Nanomaterials and Nanobiocatalyst)
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Review

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15 pages, 2882 KiB  
Review
DNA-Grafted 3D Superlattice Self-Assembly
by Shuang Wang, Xiaolin Xie, Zhi Chen, Ningning Ma, Xue Zhang, Kai Li, Chao Teng, Yonggang Ke and Ye Tian
Int. J. Mol. Sci. 2021, 22(14), 7558; https://doi.org/10.3390/ijms22147558 - 15 Jul 2021
Cited by 10 | Viewed by 4061
Abstract
The exploitation of new methods to control material structure has historically been dominating the material science. The bottom-up self-assembly strategy by taking atom/molecule/ensembles in nanoscale as building blocks and crystallization as a driving force bring hope for material fabrication. DNA-grafted nanoparticle has emerged [...] Read more.
The exploitation of new methods to control material structure has historically been dominating the material science. The bottom-up self-assembly strategy by taking atom/molecule/ensembles in nanoscale as building blocks and crystallization as a driving force bring hope for material fabrication. DNA-grafted nanoparticle has emerged as a “programmable atom equivalent” and was employed for the assembly of hierarchically ordered three-dimensional superlattice with novel properties and studying the unknown assembly mechanism due to its programmability and versatility in the binding capabilities. In this review, we highlight the assembly strategies and rules of DNA-grafted three-dimensional superlattice, dynamic assembly by different driving factors, and discuss their future applications. Full article
(This article belongs to the Special Issue Advances in Nanotechnology: Nanomaterials and Nanobiocatalyst)
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24 pages, 4064 KiB  
Review
Electrospun Nanofibers for Sensing and Biosensing Applications—A Review
by Kinga Halicka and Joanna Cabaj
Int. J. Mol. Sci. 2021, 22(12), 6357; https://doi.org/10.3390/ijms22126357 - 14 Jun 2021
Cited by 85 | Viewed by 5572
Abstract
Sensors and biosensors have found applications in many areas, e.g., in medicine and clinical diagnostics, or in environmental monitoring. To expand this field, nanotechnology has been employed in the construction of sensing platforms. Because of their properties, such as high surface area to [...] Read more.
Sensors and biosensors have found applications in many areas, e.g., in medicine and clinical diagnostics, or in environmental monitoring. To expand this field, nanotechnology has been employed in the construction of sensing platforms. Because of their properties, such as high surface area to volume ratio, nanofibers (NFs) have been studied and used to develop sensors with higher loading capacity, better sensitivity, and faster response time. They also allow to miniaturize designed platforms. One of the most commonly used techniques of the fabrication of NFs is electrospinning. Electrospun NFs can be used in different types of sensors and biosensors. This review presents recent studies concerning electrospun nanofiber-based electrochemical and optical sensing platforms for the detection of various medically and environmentally relevant compounds, including glucose, drugs, microorganisms, and toxic metal ions. Full article
(This article belongs to the Special Issue Advances in Nanotechnology: Nanomaterials and Nanobiocatalyst)
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