Anticancer and Chemopreventive Activity of Coumarins and Their Derivatives
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 30 December 2024 | Viewed by 163
Special Issue Editor
Interests: pharmacognosy; phytochemistry; natural products; HPLC; secondary metabolites; coumarins; flavonoids; phenolic acids; antioxidant activity; glycosides; LC-MS; antioxidants; anticancer activity
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Special Issue Information
Dear Colleagues,
Currently, there is a shift towards natural medicine and the exploration of compounds of natural origin as active substances in the treatment of various diseases, including cancer, as a powerful alternative to synthetic drugs.
Coumarins, secondary plant metabolites found in families of higher plants such as Apiaceae, Rutaceae, and Moraceae, exert anticancer and chemopreventive effects thanks to their ability to induce apoptosis, influence specific signaling pathways, inhibit tumour resistance to conventional drugs by acting as adjuvants, effect angiogenesis inhibition, as well act as antimetastatic drugs. These and many other activities can be enhanced by modifying their structure, e.g., by introducing new functional groups, which lead to the synthesis of coumarin derivatives.
In this Special Issue, we encourage researchers to share their latest discoveries on the anticancer and chemopreventive effects of coumarin compounds from natural sources, as well as their synthetic derivatives. New information on the mechanisms of action of coumarin compounds is especially welcome.
Entries related to the topic of this Special Issue do not have to be limited to the areas listed in the keywords. We look forward to receiving your contributions.
Dr. Magdalena Bartnik
Guest Editor
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Keywords
- coumarins
- coumarin derivatives
- anticancer activity
- chemopreventive activity
- therapy adjuvant
- mechanism of action
- in vitro and in vivo studies
- molecular research
- metabolic pathway
- phytochemicals
- natural products
- apoptosis
- bioactivity assessment
- chemical composition
- therapeutic targets
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