Advanced Molecular Research on Chronic Heart Failure
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 November 2024 | Viewed by 1505
Special Issue Editor
Interests: heart failure; atrial fibrillation; cardiovascular medicine; cardiology; ultrasound; internal medicine; chronic heart failure; clinical practice
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Chronic heart failure (CHF) is a complex clinical syndrome characterized by the heart's incapacity to effectively pump blood throughout the body to fulfill its metabolic requirements. It remains a significant challenge in cardiovascular medicine, affecting millions worldwide. Despite advances in treatment, the complex molecular mechanisms underlying CHF require further elucidation to develop targeted therapies and improve patient outcomes.
Moreover, various studies have suggested that almost 30–70% of HF patients have heart failure with preserved ejection fraction (HF-pEF), a complex clinical syndrome which is becoming a widespread challenge for daily clinical practice. In particular, amyloid infiltration of the myocardium, also called cardiac amyloidosis (CA), which has previously been considered a rare pathology, actually seems to be underestimated, resulting in approximately 15% of patients with HF-pEF.
This Special Issue aims to gather research on advanced molecular approaches to understanding and managing the disease. Submissions should address the intersection of molecular research with clinical practice, aiming to drive the field of cardiovascular medicine toward a more effective management of CHF. Topics of interest include, but are not limited to, the molecular pathways implicated in the pathogenesis of CHF disease, novel molecular imaging techniques for assessing cardiac function in CHF, biomarkers for early detection and prognosis of CHF, translational approaches of molecular research, clinical practice in CHF management and novel pharmacological treatment. Finally, extended consideration of CA should be made, a current emerging challenge in daily clinical practice and one of the most frequent causes of heart failure with preserved ejection fraction.
Dr. Marco Tana
Guest Editor
Manuscript Submission Information
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Keywords
- chronic heart failure (CHF)
- cardiovascular medicine
- cardiac amyloidosis
- biomarkers
- translational ap-proaches
- molecular approaches
- pharmacological treatment
- molecular mechanisms
- molecular pathways
- prognosis
- clinical practice in CHF management
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