Ferroptosis Mechanisms and Bone Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 28 February 2025 | Viewed by 79
Special Issue Editor
Interests: disc disease; pain mechanism; cell signaling; animal experiments; epigenetics; temporomandibular disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Ferroptosis, a regulated form of cell death, is characterized by iron-dependent accumulation and lipid peroxidation. It is closely related to multiple biological processes, including iron metabolism, polyunsaturated fatty acid metabolism, and the biosynthesis of compounds with antioxidant activities, including glutathione. Recent studies have shown that ferroptosis is important in regulating the occurrence and development of bone-related diseases, but its underlying mechanisms are not completely clear.
This Special Issue will focus on the role of ferroptosis in the pathophysiology and treatment of common bone diseases (namely bone marrow damage, osteoporosis, osteoarthritis, osteosarcoma, etc.), which will open up new avenues for the prevention and treatment of orthopedic diseases. Original research and review articles are particularly welcome in this Special Issue.
Dr. Chundo Oh
Guest Editor
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Keywords
- ferroptosis
- cell death
- iron accumulation
- lipid peroxidation
- bone-related diseases
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